DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Regnase-1 and khnyn

DIOPT Version :9

Sequence 1:	NP_650863.3	Gene:	Regnase-1 / 42394	FlyBaseID:	FBgn0038769	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002934330.2	Gene:	khnyn / 100497056	XenbaseID:	XB-GENE-1219052	Length:	841	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	105/256 - (41%)
Similarity:	152/256 - (59%)	Gaps:	27/256 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 NSSG---LRHIVIDGSNVALSHGNNLVFSCRGIRICVDWFRQRGHRDITAFVPNWRKEMANNNIA 189
            |..|   ||:|:|||||||:.||.:..||||||.:.|.:|..||||.||.|||.||.: .::.:.
Frog   579 NEKGNEELRYIIIDGSNVAMIHGLHRFFSCRGIALAVQYFWDRGHRGITVFVPQWRMK-KDSKVK 642

  Fly   190 DQELLYELEHERYLVFTPSRHLDGKRVSCYDDRFILKLAVETDGIVVSNDNYRDLILESNEFRRV 254
            :|..|.||.....|.|||||.::||||:.|||||:|:||.:|||::|:|||.||:..||..::.:
Frog   643 EQHFLTELNDLGLLSFTPSRTIEGKRVTSYDDRFMLQLAEKTDGVIVTNDNLRDIAAESQAWKTI 707

  Fly   255 VQERLLMYSFVNDIFMPPDDPLGRSGPNLDLFLCS----QTQQK---MADAQQLCPYGKKCTYGQ 312
            :::|||.|:||.||||.|||||||:||.|:.||..    :|:.|   .|..:......||.:..:
Frog   708 IKDRLLQYTFVGDIFMVPDDPLGRNGPPLNQFLSKNLRPRTKSKGHSFAGRRGTHSAPKKSSQTE 772

  Fly   313 KCKFRHHNQAPLLQRLPLQASHSAPLHT-NGGQQL------VSPGGNNNNVKINSLISREP 366
            ...||......:|:      ...|.:.: |..|:|      :.|   :.:.|::.::.|||
Frog   773 VLNFRDRKAGAVLE------ERKADVRSFNETQRLRHELLNIFP---SQDSKVDYILHREP 824

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Regnase-1	NP_650863.3	RNase_Zc3h12a	131..284	CDD:288804	84/155 (54%)
khnyn	XP_002934330.2	KH-I	18..88	CDD:412160
		KH-I	90..155	CDD:412160
		RNase_Zc3h12a	585..738	CDD:403256	84/153 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D335949at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12876
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020