DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and ZNF764

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_219363.2 Gene:ZNF764 / 92595 HGNCID:28200 Length:408 Species:Homo sapiens


Alignment Length:487 Identity:111/487 - (22%)
Similarity:167/487 - (34%) Gaps:153/487 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 RECGGVPIKQFDHYPDKICEK---CFKVLKMAFKFRETCQRSYGHLRQF-VG---PV-------E 101
            ||.|.|.......|   .|.:   |.:..:.|. :|:..:.:||||... :|   |.       |
Human    21 REPGAVSFADVAVY---FCREEWGCLRPAQRAL-YRDVMRETYGHLSALGIGGNKPALISWVEEE 81

  Fly   102 VEQRPPEKKGSETATKLEPDVDPDEAEQEPEHDEEDEDVDLDESHYAEADDAAETQGGVFHDEIE 166
            .|...|..:..|.| |.:...||.::..:.:..:.:....|:     :.|..|....|       
Human    82 AELWGPAAQDPEVA-KCQTQTDPADSRNKKKERQREGTGALE-----KPDPVAAGSPG------- 133

  Fly   167 DGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETYEGDLIPDQGYDHEMADQALSELSAEIEYL 231
                          :|:.|....|                 |..|:                   
Human   134 --------------LKSPQAPSAG-----------------PPYGW------------------- 148

  Fly   232 DQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATKRRVNPRR------SATSTAS 290
                 :||:::.|..                   |.|:.|..... |.:.|.      .:.:..|
Human   149 -----EQLSKAPHRG-------------------RPSLCAHPPVP-RADQRHGCYVCGKSFAWRS 188

  Fly   291 VAVESSTSKT-------TDRGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLARKHSGIKTKGGH 348
            ..||...|.|       ||.|.          ..|...|:...:.|..||   |.|.        
Human   189 TLVEHVYSHTGEKPFHCTDCGK----------GFGHASSLSKHRAIHRGE---RPHR-------- 232

  Fly   349 KILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGN 413
                         |..||..:..:|.||.|::||:|.||:.|..||..|:|:..|.:|...|:|.
Human   233 -------------CLECGRAFTQRSALTSHLRVHTGEKPYGCADCGRRFSQSSALYQHRRVHSGE 284

  Fly   414 RPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCG 478
            .|:.|..|..|||..|...:|.|.||.|:||.|..|.:.|..::.:..|:..|:||||:.|..||
Human   285 TPFPCPDCGRAFAYPSDLRRHVRTHTGEKPYPCPDCGRCFRQSSEMAAHRRTHSGEKPYPCPQCG 349

  Fly   479 KGFPQAYKLRNHRVIHERRGQSARESVAGLVS 510
            :.|.|...:..|:.:|.......|..|||.:|
Human   350 RRFGQKSAVAKHQWVHRPGAGGHRGRVAGRLS 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871 13/46 (28%)
C2H2 Zn finger 362..382 CDD:275368 7/19 (37%)
zf-H2C2_2 375..399 CDD:290200 12/23 (52%)
COG5048 386..>447 CDD:227381 25/60 (42%)
C2H2 Zn finger 390..410 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 8/22 (36%)
C2H2 Zn finger 418..438 CDD:275368 8/19 (42%)
zf-H2C2_2 432..455 CDD:290200 10/22 (45%)
C2H2 Zn finger 446..466 CDD:275368 4/19 (21%)
zf-H2C2_2 459..481 CDD:290200 9/21 (43%)
C2H2 Zn finger 474..494 CDD:275368 6/19 (32%)
ZNF764NP_219363.2 zf-H2C2_2 301..326 CDD:290200 10/24 (42%)
C2H2 Zn finger 317..337 CDD:275368 4/19 (21%)
zf-H2C2_2 333..352 CDD:290200 9/18 (50%)
C2H2 Zn finger 345..365 CDD:275368 6/19 (32%)
KRAB 26..85 CDD:214630 14/62 (23%)
KRAB 26..65 CDD:279668 10/42 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 91..167 20/162 (12%)
C2H2 Zn finger 177..197 CDD:275368 3/19 (16%)
zf-H2C2_2 190..212 CDD:290200 7/31 (23%)
C2H2 Zn finger 205..225 CDD:275368 5/29 (17%)
zf-H2C2_2 217..242 CDD:290200 9/48 (19%)
COG5048 229..>294 CDD:227381 26/85 (31%)
C2H2 Zn finger 233..253 CDD:275368 7/19 (37%)
zf-H2C2_2 245..270 CDD:290200 12/24 (50%)
C2H2 Zn finger 261..281 CDD:275368 7/19 (37%)
zf-H2C2_2 273..298 CDD:290200 9/24 (38%)
COG5048 285..>350 CDD:227381 25/64 (39%)
C2H2 Zn finger 289..309 CDD:275368 8/19 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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