Protein Alignment idc and ZNF208

DIOPT Version :10

• Sequence 1: NP_650862.1
• Gene: idc / 42393
• FlyBaseID: FBgn0038768
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_009084.2
• Gene: ZNF208 / 7757
• HGNCID: 12999
• Length: 1280
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 113/387 - (29%)
• Similarity: 161/387 - (41%)
• Gaps: 82/387 - (21%)

  Fly   169 ILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETYEGDLIPDQGYDHEMADQAL--------SELS 225
            |.:|..|:.....::|.|||..:|      ...:..||.|:||.:.......|        ..|.
Human    54 IFLEEGKESWNMKRHEMVEESPVI------CSHFAQDLWPEQGIEDSFQKVILRRYEKCGHENLH 112

  Fly   226 AEIEYLDQVE-------HDQLTESAHEDDAEVDLNSTEEEFVP-----------SKSVRASIHAR 272
            .:|.|.:..|       :::|.:|         |.:|:.:...           |.|.|..|  |
Human   113 LKIGYTNVDECKVHKEGYNKLNQS---------LTTTQSKVFQRGKYANVFHKCSNSNRHKI--R 166

  Fly   273 NATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLKVRRGNS----------------------- 314
            :..|:.:..:....|...::..|...:...|.|..|...|..
Human   167 HTGKKHLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRC 231

  Fly   315 ---DSAGSKMSIKSE-KDISIGEV--------LARKHSGIKTKGGHKILLGDKKEFKYICDVCGN 367
               ..|.||.||.:: |.|..||.        .|...|.|.||  |||:...:|..|  |:.||.
Human   232 KECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTK--HKIIHTGEKPNK--CEECGK 292

  Fly   368 MYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRN 432
            .:...|.||.|..:|:|.||::|:.||..|::...|..|...|.|.:||||..|..||:..|...
Human   293 AFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILT 357

  Fly   433 KHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIH 494
            ||..|||.|:||:|:.|.|.:.:.:||.:||.|||||||:.|:.|||||.....|..|.|||
Human   358 KHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIH 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
idc	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		COG5048	386..>447	CDD:227381	26/60 (43%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		SFP1	<424..491	CDD:227516	32/66 (48%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..494	CDD:275368	9/19 (47%)
ZNF208	NP_009084.2	KRAB	4..64	CDD:214630	3/9 (33%)
		C2H2 Zn finger	175..195	CDD:275368	2/19 (11%)
		C2H2 Zn finger	203..223	CDD:275368	1/19 (5%)
		COG5048	227..619	CDD:227381	79/197 (40%)
		C2H2 Zn finger	231..251	CDD:275368	6/19 (32%)
		C2H2 Zn finger	259..279	CDD:275368	8/21 (38%)
		C2H2 Zn finger	287..307	CDD:275368	7/19 (37%)
		C2H2 Zn finger	315..335	CDD:275368	6/19 (32%)
		C2H2 Zn finger	343..363	CDD:275368	7/19 (37%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	399..419	CDD:275368	9/19 (47%)
		C2H2 Zn finger	427..447	CDD:275368
		C2H2 Zn finger	455..475	CDD:275368
		C2H2 Zn finger	499..519	CDD:275368
		C2H2 Zn finger	527..547	CDD:275368
		C2H2 Zn finger	555..575	CDD:275368
		C2H2 Zn finger	583..603	CDD:275368
		C2H2 Zn finger	611..631	CDD:275368
		C2H2 Zn finger	639..659	CDD:275368
		C2H2 Zn finger	667..687	CDD:275368
		COG5048	691..1133	CDD:227381
		C2H2 Zn finger	695..715	CDD:275368
		C2H2 Zn finger	723..743	CDD:275368
		C2H2 Zn finger	751..771	CDD:275368
		C2H2 Zn finger	779..799	CDD:275368
		C2H2 Zn finger	807..827	CDD:275368
		C2H2 Zn finger	835..855	CDD:275368
		C2H2 Zn finger	863..883	CDD:275368
		C2H2 Zn finger	891..911	CDD:275368
		C2H2 Zn finger	919..939	CDD:275368
		C2H2 Zn finger	947..967	CDD:275368
		C2H2 Zn finger	976..995	CDD:275368
		C2H2 Zn finger	1003..1023	CDD:275368
		C2H2 Zn finger	1031..1051	CDD:275368
		C2H2 Zn finger	1059..1079	CDD:275368
		C2H2 Zn finger	1087..1107	CDD:275368
		C2H2 Zn finger	1115..1135	CDD:275368
		SFP1	<1137..1217	CDD:227516
		C2H2 Zn finger	1143..1163	CDD:275368
		C2H2 Zn finger	1171..1191	CDD:275368
		SFP1	<1193..1273	CDD:227516
		C2H2 Zn finger	1199..1219	CDD:275368
		C2H2 Zn finger	1227..1247	CDD:275368
		C2H2 Zn finger	1255..1275	CDD:275368