Protein Alignment idc and Zkscan14

DIOPT Version :10

• Sequence 1: NP_650862.1
• Gene: idc / 42393
• FlyBaseID: FBgn0038768
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_075811.2
• Gene: Zkscan14 / 67235
• MGIID: 1914485
• Length: 521
• Species: Mus musculus
• Alignment Length: 499
• Identity: 123/499 - (24%)
• Similarity: 182/499 - (36%)
• Gaps: 109/499 - (21%)

  Fly    84 ETCQRSYGHLR--QFVGPVEVEQR---------PPEKKGSET----------ATKLEPDVDPDEA 127
            ||.::.:..||  :..||.|...|         .||....|.          .|.|..::.....
Mouse    41 ETSRKQFRQLRYQEVAGPEEALSRLWELCRRWLRPELLSKEQIMELLVLEQFLTILPQELQAYVR 105

  Fly   128 EQEPEHDEEDEDVDLDESHYAEADDAAETQGGVFHDEIEDGILVELEKDRIVHVK----NEQVEE 188
            :..||..||...:   ......|.|.|..||.:...::.:.:..| |.:::...:    .|..::
Mouse   106 DHSPESGEEAAAL---ARTLQRALDRASPQGFMTFKDVAESLTWE-EWEQLAAARKGFCEESTKD 166

  Fly   189 DGIIEEVYDVYE--TYEGDLIPDQGYDHEMADQALSELSAEIEYLDQVEHDQLTESAHEDDAEVD 251
            .|  ..|....|  |...|:|..|....|...||         :|.:|....:.......|...|
Mouse   167 AG--STVVPGLETRTVNTDVILKQEILKEAEPQA---------WLQEVSQGMVPALTKCGDPSED 220

  Fly   252 LNSTEEEFVPSKSVRASIHARNATKRRVNPRRSATSTA---SVAVESSTSKTTDRGNPLKVRRG- 312
            .    ||.:|..:|...:.......|...|.....|..   |...||..|.::..|..::...|
Mouse   221 W----EEKLPKAAVLLQLQGSEEQGRTAIPLLIGVSREERDSKNNESENSGSSVLGQHIQTAEGL 281

  Fly   313 --NSDSAGSKM--------SIK--SEKDISIGEVLARK-------------HSGIKTKGG----H 348
              ||.......        |:|  |..|.::|.:..::             ..|.:.:..    .
Mouse   282 GTNSQCGDDHKQGFHVKCHSVKPHSSVDSAVGLLETQRQFQEDKPYKCDSCEKGFRQRSDLFKHQ 346

  Fly   349 KILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHT-- 411
            :|..|:|   .|.|..||..:...:.|.:|.:.|:|.||:.|..||.||.|:..|:||..||.
Mouse   347 RIHTGEK---PYQCQECGKRFSQSAALVKHQRTHTGEKPYACPECGECFRQSSHLSRHQRTHASE 408

  Fly   412 -------------------------GNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHK 451
                                     |.|||||..|..:|...|...||.|.||.|:||.|.||.:
Mouse   409 KYYKCEECGEIVHVSSLFRHQRLHRGERPYKCGDCEKSFRQRSDLFKHQRTHTGEKPYACVVCGR 473

  Fly   452 TFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHE 495
            .|:.:.||..|:..||||||:.|..||:.|.|:..|..|:.||:
Mouse   474 RFSQSATLIKHQRTHTGEKPYKCFQCGERFRQSTHLVRHQRIHQ 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
idc	NP_650862.1	zf-AD	22..95	CDD:214871	4/12 (33%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		COG5048	386..>447	CDD:227381	30/87 (34%)
		C2H2 Zn finger	390..410	CDD:275368	9/19 (47%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		SFP1	<424..491	CDD:227516	29/66 (44%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..494	CDD:275368	7/19 (37%)
Zkscan14	NP_075811.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		2/3 (67%)
		SCAN	40..151	CDD:128708	24/113 (21%)
		KRAB	135..193	CDD:214630	10/60 (17%)
		COG5048	<303..484	CDD:227381	52/183 (28%)
		C2H2 Zn finger	329..349	CDD:275368	1/19 (5%)
		C2H2 Zn finger	357..377	CDD:275368	5/19 (26%)
		C2H2 Zn finger	385..405	CDD:275368	9/19 (47%)
		C2H2 Zn finger	440..460	CDD:275368	7/19 (37%)
		C2H2 Zn finger	468..488	CDD:275368	7/19 (37%)
		zf-H2C2_2	481..505	CDD:463886	12/23 (52%)
		C2H2 Zn finger	496..516	CDD:275368	7/19 (37%)