DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4936 and Zscan4f

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001103786.2 Gene:Zscan4f / 665902 MGIID:3708485 Length:506 Species:Mus musculus


Alignment Length:388 Identity:89/388 - (22%)
Similarity:131/388 - (33%) Gaps:126/388 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 EAEQEPEHDEEDEDVDLDE----------SHYAEADDAAETQGGVFHDEIEDGILVELEKDRIVH 180
            :.||.|||:|.:.......          ||:.:...|..|         .|..:.|..||    
Mouse   214 QKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTT---------ADVPMEEQPKD---- 265

  Fly   181 VKNEQVEEDGIIEEVYDVYET--------YEGDLIPDQGYDHEMADQALSELSAEIEYLDQVEHD 237
                 :..:.|.|:..:.|.|        |.||.||....|....::.:.....|:         
Mouse   266 -----LSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEV--------- 316

  Fly   238 QLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATKRRVNPRRSATSTASVAVESSTSKTTD 302
                      .::...      ||..|.|||               ..|||..            
Mouse   317 ----------GDIPYG------VPQDSTRAS---------------QGTSTCL------------ 338

  Fly   303 RGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLARKHSGIKTKG----GHKILLGDKKEFKYICD 363
                       .:|.|...   ||||       .|:..|::::.    ...:|||...|....|:
Mouse   339 -----------QESLGECF---SEKD-------PREVPGLQSRQEQLISDPVLLGKNHEANLPCE 382

  Fly   364 VCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNR-PYKCSYCPAAFAD 427
                  ..|.|.....|:      ::||.|...|..|:.|:.|..||...: ...|..|...|..
Mouse   383 ------SHQKRFCRDAKL------YKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKR 435

  Fly   428 LSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNH 490
            :|.|..|..||..|:|::|..|.|:|::...||.|:||||||.|:||.:|.:.|.|:.....|
Mouse   436 VSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRH 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 4/19 (21%)
zf-H2C2_2 375..399 CDD:290200 5/23 (22%)
COG5048 386..>447 CDD:227381 19/61 (31%)
C2H2 Zn finger 390..410 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 6/23 (26%)
C2H2 Zn finger 418..438 CDD:275368 6/19 (32%)
zf-H2C2_2 432..455 CDD:290200 9/22 (41%)
C2H2 Zn finger 446..466 CDD:275368 8/19 (42%)
zf-H2C2_2 459..481 CDD:290200 13/21 (62%)
C2H2 Zn finger 474..494 CDD:275368 5/17 (29%)
Zscan4fNP_001103786.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
SCAN <51..117 CDD:295388
zf-C2H2 395..417 CDD:278523 7/21 (33%)
C2H2 Zn finger 397..417 CDD:275368 7/19 (37%)
C2H2 Zn finger 426..446 CDD:275368 6/19 (32%)
zf-H2C2_2 438..463 CDD:290200 10/24 (42%)
C2H2 Zn finger 454..474 CDD:275368 8/19 (42%)
zf-H2C2_2 466..491 CDD:290200 14/24 (58%)
C2H2 Zn finger 482..500 CDD:275368 5/17 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.