DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and MYNN

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001172047.1 Gene:MYNN / 55892 HGNCID:14955 Length:610 Species:Homo sapiens


Alignment Length:322 Identity:88/322 - (27%)
Similarity:142/322 - (44%) Gaps:70/322 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   212 YDHEMADQALSELSAEIEYLDQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATK 276
            |..::.:.|..||..:...|.....:|:.:.  .|::|::|.|..|...|::.:   :|.....:
Human   199 YPSDILENASVELFLDANKLPTPVVEQVAQI--NDNSELELTSVVENTFPAQDI---VHTVTVKR 258

  Fly   277 RRVNPRRSATSTASVAVESSTSKTTDRGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLARKHSG 341
            :|      ..|..:.|::..:.               |:.|..|...::|..   ||.|.:::| 
Human   259 KR------GKSQPNCALKEHSM---------------SNIASVKSPYEAENS---GEELDQRYS- 298

  Fly   342 IKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARH 406
                           :.|.:|:.||.::...|.|..|:::|.||||:.|.:||..|.|..||..|
Human   299 ---------------KAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTH 348

  Fly   407 MNTHTGNRPYKCSYCPAAFADLSTRNKHHRI-HTNERPYECDVCHKTFTYTNTLKFHKMIHTGEK 470
            :.||||.:||||..|...||.......|.|: |..|:||:||||:..|..::.||.|...|:|||
Human   349 VRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEK 413

  Fly   471 PHVCDVCGKGFPQA----YKLRNHR--------------------VIHERRGQSARESVAGL 508
            |:|||.||:.|.||    |.:|.|.                    :.|.|:....:..:.|:
Human   414 PYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGI 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 6/19 (32%)
zf-H2C2_2 375..399 CDD:290200 11/23 (48%)
COG5048 386..>447 CDD:227381 27/61 (44%)
C2H2 Zn finger 390..410 CDD:275368 8/19 (42%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 418..438 CDD:275368 6/20 (30%)
zf-H2C2_2 432..455 CDD:290200 11/23 (48%)
C2H2 Zn finger 446..466 CDD:275368 8/19 (42%)
zf-H2C2_2 459..481 CDD:290200 13/21 (62%)
C2H2 Zn finger 474..494 CDD:275368 10/43 (23%)
MYNNNP_001172047.1 BTB 14..115 CDD:306997
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 169..197
Nuclear localization signal. /evidence=ECO:0000255 174..190
Nuclear localization signal. /evidence=ECO:0000255 257..262 1/10 (10%)
C2H2 Zn finger 304..324 CDD:275368 6/19 (32%)
zf-C2H2 304..324 CDD:306579 6/19 (32%)
zf-H2C2_2 316..341 CDD:316026 11/24 (46%)
C2H2 Zn finger 332..352 CDD:275368 8/19 (42%)
zf-H2C2_2 345..369 CDD:316026 12/23 (52%)
SFP1 <354..438 CDD:227516 37/83 (45%)
C2H2 Zn finger 360..380 CDD:275368 6/19 (32%)
C2H2 Zn finger 389..409 CDD:275368 8/19 (42%)
C2H2 Zn finger 417..437 CDD:275368 9/19 (47%)
zf-H2C2_2 430..453 CDD:316026 3/22 (14%)
SFP1 <439..522 CDD:227516 3/37 (8%)
C2H2 Zn finger 445..465 CDD:275368 2/19 (11%)
C2H2 Zn finger 473..493 CDD:275368 1/3 (33%)
C2H2 Zn finger 501..522 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 521..556
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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