DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and ZSCAN2

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:XP_024305746.1 Gene:ZSCAN2 / 54993 HGNCID:20994 Length:645 Species:Homo sapiens


Alignment Length:517 Identity:126/517 - (24%)
Similarity:197/517 - (38%) Gaps:114/517 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 QKWIVCRVCLQQ------PKEPMASIFN---DDSE------KDLTHMIRECGGVPIKQFDHYPDK 67
            ::|:...|..::      |||..|.:..   :.||      :|||..:::.|    .|..|.|  
Human    85 RRWLRPEVHTKEQMLTMLPKEIQAWLQEHRPESSEEAAALVEDLTQTLQDSG----SQRVHQP-- 143

  Fly    68 ICEKCFKVLKMAFKFRETCQRSYG-HLRQFVGPVEVEQRPPEKKGSETATKLEPDVDPDEAE--- 128
                 |.||.:......:.:|:.. ||..|    |::        ||.......|:..:|:.   
Human   144 -----FSVLTVCKVSSRSARRALELHLNYF----EIQ--------SENGENCNQDMFENESRKIF 191

  Fly   129 ------QEPEHDEEDEDVDLDESHYAEADDAAETQGGVFHDEIEDGILVELEKDRIVHVKNEQVE 187
                  :..:|.:.:.|.:.|..       ....||   |...||              ..|.|.
Human   192 SEMPEGESAQHSDGESDFERDAG-------IQRLQG---HSPGED--------------HGEVVS 232

  Fly   188 EDGIIEEVYDVYETYEGDLIPDQGYDHEMADQALSELSAEIEYLDQVEHDQLTESAHEDDAEVDL 252
            :|..:.::..:..||.|    ::.|:.....:..|..|..|.:          |..|..:.....
Human   233 QDREVGQLIGLQGTYLG----EKPYECPQCGKTFSRKSHLITH----------ERTHTGEKYYKC 283

  Fly   253 NSTEEEFVPSKSVRASIHARNATKRRVNPRRSATSTASVAVESSTSKTTDRG-NPLKVRR-GNSD 315
            :...:.|  |.....|.|....|..:....|....:.|.:....|.:....| .|.:... |.|.
Human   284 DECGKSF--SDGSNFSRHQTTHTGEKPYKCRDCGKSFSRSANLITHQRIHTGEKPFQCAECGKSF 346

  Fly   316 SAGSKM-----SIKSEKDISIGEV--------LARKHSGIKTKGGHKILLGDKKEFKYICDVCGN 367
            |....:     :...||..|..|.        ....|.||.|        |:|   .|.|..||.
Human   347 SRSPNLIAHQRTHTGEKPYSCPECGKSFGNRSSLNTHQGIHT--------GEK---PYECKECGE 400

  Fly   368 MYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRN 432
            .:...|.|..|.::|:|.||::|..||..|:|:..|..|..||||.:||:||.|..:|:..|...
Human   401 SFSYNSNLIRHQRIHTGEKPYKCTDCGQRFSQSSALITHRRTHTGEKPYQCSECGKSFSRSSNLA 465

  Fly   433 KHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIH 494
            .|.|.|..|:||:|.||.|:|:.:::|..|:.:||||||:.|..||:.|..:..|..|:.||
Human   466 THRRTHMVEKPYKCGVCGKSFSQSSSLIAHQGMHTGEKPYECLTCGESFSWSSNLLKHQRIH 527

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871 20/88 (23%)
C2H2 Zn finger 362..382 CDD:275368 6/19 (32%)
zf-H2C2_2 375..399 CDD:290200 10/23 (43%)
COG5048 386..>447 CDD:227381 26/60 (43%)
C2H2 Zn finger 390..410 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 418..438 CDD:275368 7/19 (37%)
zf-H2C2_2 432..455 CDD:290200 11/22 (50%)
C2H2 Zn finger 446..466 CDD:275368 7/19 (37%)
zf-H2C2_2 459..481 CDD:290200 11/21 (52%)
C2H2 Zn finger 474..494 CDD:275368 6/19 (32%)
ZSCAN2XP_024305746.1 SCAN 70..157 CDD:322011 18/82 (22%)
COG5048 251..631 CDD:227381 85/300 (28%)
C2H2 Zn finger 255..275 CDD:275368 4/29 (14%)
C2H2 Zn finger 283..303 CDD:275368 4/21 (19%)
C2H2 Zn finger 311..331 CDD:275368 3/19 (16%)
C2H2 Zn finger 339..359 CDD:275368 3/19 (16%)
C2H2 Zn finger 367..387 CDD:275368 3/19 (16%)
C2H2 Zn finger 395..415 CDD:275368 6/19 (32%)
C2H2 Zn finger 423..443 CDD:275368 7/19 (37%)
C2H2 Zn finger 451..471 CDD:275368 7/19 (37%)
C2H2 Zn finger 479..499 CDD:275368 7/19 (37%)
C2H2 Zn finger 507..527 CDD:275368 6/19 (32%)
C2H2 Zn finger 535..555 CDD:275368
C2H2 Zn finger 563..583 CDD:275368
C2H2 Zn finger 591..611 CDD:275368
C2H2 Zn finger 619..639 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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