Protein Alignment idc and Zfp213

DIOPT Version :10

• Sequence 1: NP_650862.1
• Gene: idc / 42393
• FlyBaseID: FBgn0038768
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001028668.2
• Gene: Zfp213 / 449521
• MGIID: 3053094
• Length: 468
• Species: Mus musculus
• Alignment Length: 505
• Identity: 118/505 - (23%)
• Similarity: 188/505 - (37%)
• Gaps: 105/505 - (20%)

  Fly    31 KEPMASIFNDDSE----KDLTHMIRECGGVPIKQFDHYPDKICEKCFKVLKMAFKFRETCQRSYG 91
            :||:..:.:.|||    :......|:.|| |.:.|    .::.|.|.:.|:.....:|......
Mouse    30 QEPVQPVDSRDSEACRQRFRQFCFRDAGG-PHEAF----SQLWELCCRWLRPELHSKEQILELL- 88

  Fly    92 HLRQFV----GPVEVEQRPPEKKGSETATKLEPDVDPDEAEQEPEHDEEDEDVDLDESHYAEADD 152
            .|.||:    |.::.:.:.......|.|..|..|:.....:..|:          ||  .:||:.
Mouse    89 VLEQFLAVLPGEIQAQLQRQHLGSGEEAVALVEDIQNQSLKAWPQ----------DE--LSEAEP 141

  Fly   153 AAETQG----------GVFHDEIEDGILVELEKDR----IVHVKNEQVEE--DGIIEEVYDVYET 201
            .|..||          ||...      |..|:..|    :..:|..|..|  ||..:...|:...
Mouse   142 KAAVQGLQATGSPQKTGVQKQ------LPALQGQRSHAQLPVLKERQTGEVLDGCFDSAVDLPGR 200

  Fly   202 YE-GDLIPDQGYDHEMADQALSELSAEIEYLDQVEHDQL--TESAHEDDAEVDLNSTEEEFVPSK 263
            .| |.:.|.| ....:.|........|...||..:.:..  .:..:..||.:.|....:: .|::
Mouse   201 PELGRISPFQ-KSGSLGDIPFYCSREEWSSLDPAQRNLFWNIKRKNSRDAALGLRPKSQK-PPAE 263

  Fly   264 SVRASIHARNATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLK--------VRRGNSDSAGSK 320
            ....::..:.......||            |.:.::..:..||::        .|||...:...:
Mouse   264 EAATALLGQTEVPMSWNP------------EEAETEVWESENPMRTALDPLVGARRGRPPTHRRQ 316

  Fly   321 MSIKSEKDISIGEVLARK-HSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSG 384
            ..          .:||.| ||                     |..||..:...|.|..|.:.|:|
Mouse   317 FQ----------NLLAEKPHS---------------------CAQCGKRFRWGSDLARHQRTHTG 350

  Fly   385 VKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVC 449
            .|||:|..|...|..:..|.||...|||.:|:.||.|..:|:..:....|.||||.|:|:.|..|
Mouse   351 EKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFSCSEC 415

  Fly   450 HKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHERRGQ 499
            .|:|...:.|..|:.:||||:|..|..|.|.|.|...|..|:.:|.:..|
Mouse   416 GKSFALRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQSLHSKMAQ 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
idc	NP_650862.1	zf-AD	22..95	CDD:214871	15/67 (22%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		COG5048	386..>447	CDD:227381	24/60 (40%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		SFP1	<424..491	CDD:227516	25/66 (38%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..494	CDD:275368	7/19 (37%)
Zfp213	NP_001028668.2	SCAN	41..138	CDD:128708	22/114 (19%)
		KRAB_A-box	214..247	CDD:143639	4/32 (13%)
		COG5048	<324..461	CDD:227381	53/157 (34%)
		C2H2 Zn finger	328..348	CDD:275368	6/19 (32%)
		C2H2 Zn finger	356..376	CDD:275368	6/19 (32%)
		C2H2 Zn finger	384..404	CDD:275368	6/19 (32%)
		C2H2 Zn finger	412..432	CDD:275368	6/19 (32%)
		C2H2 Zn finger	440..460	CDD:275368	7/19 (37%)