DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4936 and CG1792

DIOPT Version :9

Sequence 1:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	81/302 - (26%)
Similarity:	129/302 - (42%)	Gaps:	56/302 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 SELSAEIEYLDQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATKRRVNPRRSAT 286
            :|...|||.:|.:..:.|.|...|.....:.|...:..||::..:.              |||..
  Fly   104 AEEVTEIEVIDLLPEEHLLEETEEPYEICEQNEQPQVKVPAQEKKL--------------RRSTK 154

  Fly   287 STASVAVESSTSKTTDRGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLARKHSGIKTKGGHKIL 351
            :|.:|   .::.|..|          ||.:..::.|..:|     .||:|.|.
  Fly   155 TTPTV---FTSVKFAD----------NSQATRTQWSRLTE-----DEVVALKR------------ 189

  Fly   352 LGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPY 416
              ::::...||:.||..:...|....|:..|:|||...|:.|...|..|..|.||...|.||..:
  Fly   190 --ERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALF 252

  Fly   417 KCSYCPAAFADLSTRNKHHRI-HTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKG 480
            :|.||.|.:::.|.|.:|.|: |||.:|:.|..|:|:|..:..|:.|.:.|||.:...||.|...
  Fly   253 QCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVS 317

  Fly   481 FPQAYKLRNHRVIHER-RGQSARESVAGLVSYDTANIVGLDM 521
            |.:    |:|...|.| :|.:...|....:.    |.|.||:
  Fly   318 FVR----RSHLTSHYRSKGHAHTSSAQAALD----NPVELDV 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		zf-H2C2_2	375..399	CDD:290200	8/23 (35%)
		COG5048	386..>447	CDD:227381	23/61 (38%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		zf-H2C2_2	403..426	CDD:290200	10/22 (45%)
		C2H2 Zn finger	418..438	CDD:275368	8/20 (40%)
		zf-H2C2_2	432..455	CDD:290200	10/23 (43%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		zf-H2C2_2	459..481	CDD:290200	8/21 (38%)
		C2H2 Zn finger	474..494	CDD:275368	6/19 (32%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		C2H2 Zn finger	226..243	CDD:275368	6/16 (38%)
		C2H2 Zn finger	254..275	CDD:275368	8/20 (40%)
		zf-C2H2	281..303	CDD:278523	6/21 (29%)
		C2H2 Zn finger	283..303	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..320	CDD:290200	9/23 (39%)
		C2H2 Zn finger	311..329	CDD:275368	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960