DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4936 and ZNF793

DIOPT Version :9

Sequence 1:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001013681.2	Gene:	ZNF793 / 390927	HGNCID:	33115	Length:	406	Species:	Homo sapiens

Alignment Length:	174	Identity:	67/174 - (38%)
Similarity:	92/174 - (52%)	Gaps:	6/174 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 GEVLARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHC 396
            |:....|...|:.:..|   .|:|   .|.|..||..:..:|.|.:|.::|:||:|.||..||..
Human   233 GKAFCYKSEFIRHQRSH---TGEK---PYGCTDCGKAFSHKSTLIKHQRIHTGVRPFECFFCGKA 291

  Fly   397 FAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKF 461
            |.|......|..||||.||:.||.|..:|.:.|..|.|.::||.||||.|..|.|:|:..:.|..
Human   292 FTQKSHRTEHQRTHTGERPFVCSECGKSFGEKSYLNVHRKMHTGERPYRCRECGKSFSQKSCLNK 356

  Fly   462 HKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHERRGQSARESV 505
            |...||||||:.|:.|||.|.|...|..|:.||.|:.....|::
Human   357 HWRTHTGEKPYGCNECGKAFYQKPNLSRHQKIHARKNAYRNENL 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		zf-H2C2_2	375..399	CDD:290200	11/23 (48%)
		COG5048	386..>447	CDD:227381	27/60 (45%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	10/22 (45%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		zf-H2C2_2	432..455	CDD:290200	12/22 (55%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		zf-H2C2_2	459..481	CDD:290200	12/21 (57%)
		C2H2 Zn finger	474..494	CDD:275368	8/19 (42%)
ZNF793	NP_001013681.2	KRAB	8..68	CDD:214630
		C2H2 Zn finger	190..221	CDD:275368
		COG5048	<225..385	CDD:227381	62/157 (39%)
		C2H2 Zn finger	229..249	CDD:275368	3/15 (20%)
		C2H2 Zn finger	257..277	CDD:275368	6/19 (32%)
		C2H2 Zn finger	285..305	CDD:275368	6/19 (32%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		C2H2 Zn finger	341..361	CDD:275368	6/19 (32%)
		C2H2 Zn finger	369..389	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910