DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4936 and Zbtb6

DIOPT Version :9

Sequence 1:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001102423.1	Gene:	Zbtb6 / 366029	RGDID:	1306007	Length:	423	Species:	Rattus norvegicus

Alignment Length:	404	Identity:	86/404 - (21%)
Similarity:	147/404 - (36%)	Gaps:	110/404 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 FVGPVEVEQRPPEK---------------KGSETATK-LEPDVDPDEAEQEPEHDEEDEDVDLDE 144
            :.|.:||:::...|               |.:|..:| ||.|:    :.:..:|.:..:..|.|.
  Rat    89 YTGALEVKRKELLKYLTAASYLQMVHIVEKCTEALSKYLEIDL----SMKNNQHTDLCQSSDTDV 149

  Fly   145 SHYAEADDAAETQGGVFHDEIEDGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETYEGDLIPD 209
            .:..|..|             :|..::|:.:|..|::.....||:|  :.:....||...:....
  Rat   150 KNEEENSD-------------KDCEIIEISEDSPVNLDPPVKEEEG--DALQSAAETLTSERRGV 199

  Fly   210 QGYDHEMADQALSE-----LSAEIEYLDQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASI 269
            :..:....|....|     |..|..:.|.:|:.|..:.....:|.:....|:...:
  Rat   200 KSPELSTVDGGFKENEICILHVESIHTDDIENGQFPQPCTSSNAGMYFPETQHSVI--------- 255

  Fly   270 HARNATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLKVRRG----NSDSAGSKMSIKSEKDIS 330
               |:|                 ||:..::.     |....:|    |||  ||..:|...:::.
  Rat   256 ---NST-----------------VENRVTEV-----PGNTNQGLFSENSD--GSHGTINEIQNLD 293

  Fly   331 IGEVLARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGH 395
              |..:.:|.                     |..|...:........|:|:|   |...|..||.
  Rat   294 --ENFSLRHQ---------------------CPRCPRGFLHVENYLRHLKMH---KLFLCLQCGK 332

  Fly   396 CFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLK 460
            .|.|.:.|.||:..|.|.||::|:.|...|...||...|..||:.:|||:|..|...|.:.:.||
  Rat   333 TFTQKKNLNRHIRGHMGIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKCHCCDMDFKHKSALK 397

  Fly   461 FH-KMIH---TGEK 470
            .| ..:|   :|||
  Rat   398 KHLTSVHGRSSGEK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	4/19 (21%)
		zf-H2C2_2	375..399	CDD:290200	8/23 (35%)
		COG5048	386..>447	CDD:227381	24/60 (40%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		zf-H2C2_2	403..426	CDD:290200	9/22 (41%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		zf-H2C2_2	432..455	CDD:290200	9/22 (41%)
		C2H2 Zn finger	446..466	CDD:275368	6/20 (30%)
		zf-H2C2_2	459..481	CDD:290200	7/16 (44%)
		C2H2 Zn finger	474..494	CDD:275368
Zbtb6	NP_001102423.1	BTB_POZ_ZBTB6	8..123	CDD:349506	6/33 (18%)
		COG5048	<251..>398	CDD:227381	47/208 (23%)
		C2H2 Zn finger	302..322	CDD:275368	4/19 (21%)
		zf-C2H2	325..347	CDD:395048	8/21 (38%)
		C2H2 Zn finger	327..347	CDD:275368	8/19 (42%)
		zf-H2C2_2	339..363	CDD:404364	9/23 (39%)
		C2H2 Zn finger	355..375	CDD:275368	6/19 (32%)
		C2H2 Zn finger	383..400	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910