Protein Alignment idc and ZSCAN22

DIOPT Version :10

• Sequence 1: NP_650862.1
• Gene: idc / 42393
• FlyBaseID: FBgn0038768
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_862829.1
• Gene: ZSCAN22 / 342945
• HGNCID: 4929
• Length: 491
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 123/444 - (27%)
• Similarity: 178/444 - (40%)
• Gaps: 93/444 - (20%)

  Fly    93 LRQFVG--PVEVE-----QRPPEKKGSETATKLE------------PDVDPDEAEQEPEHDEEDE 138
            |.||:|  |.|::     |.|  |.|.|.|..:|            |..:|.||..:..
Human    94 LEQFLGALPPEIQAWVGAQSP--KSGEEAAVLVEDLTQVLDKRGWDPGAEPTEASCKQS------ 150

  Fly   139 DVDLDESHYAEADDAAET-QGGVFHDEIEDGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETY 202
              ||.||   |..:..|| .|||   .:....:...|.:       ...|..|:..|::....|.
Human   151 --DLGES---EPSNVTETLMGGV---SLGPAFVKACEPE-------GSSERSGLSGEIWTKSVTQ 200

  Fly   203 EGDLIPDQG-YDHEMADQALSELSAEIEYLDQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVR 266
            :.......| |.....||...|                 ..|..:.:....|.|.:|..||:...
Human   201 QIHFKKTSGPYKDVPTDQRGRE-----------------SGASRNSSSAWPNLTSQEKPPSEDKF 248

  Fly   267 ASIHARN-------ATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLKVRR-GNSDSAGSKMS- 322
            ..:.|..       :.||....|.......|.:...:..||..|..|..... |.:.|..:.::
Human   249 DLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQ 313

  Fly   323 -------IKSEKDISIGEVLAR-----KHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRL 375
                   .|..:....|:..:|     :|..|.|        |:|   .|.|..||..:...:.|
Human   314 HQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHT--------GEK---PYKCGECGKTFSRSTHL 367

  Fly   376 TEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTN 440
            |:|.:||:|.:|:||:.||..|:|:..|.:|...|||.:||||..|..||:|.|...:|.|||:.
Human   368 TQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSG 432

  Fly   441 ERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIH 494
            |:||:|.||.|.|..:::|..|:.|||||||:.|..|||.|.::..|..|..||
Human   433 EKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIH 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
idc	NP_650862.1	zf-AD	22..95	CDD:214871	1/1 (100%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		COG5048	386..>447	CDD:227381	28/60 (47%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		SFP1	<424..491	CDD:227516	31/66 (47%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..494	CDD:275368	7/19 (37%)
ZSCAN22	NP_862829.1	C2H2 Zn finger	410..430	CDD:275368	8/19 (42%)
		C2H2 Zn finger	438..458	CDD:275368	7/19 (37%)
		C2H2 Zn finger	466..486	CDD:275368	7/19 (37%)
		SCAN	45..133	CDD:460417	13/40 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..161		9/37 (24%)
		COG5048	<174..482	CDD:227381	93/342 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..249		11/61 (18%)
		C2H2 Zn finger	270..290	CDD:275368	3/19 (16%)
		C2H2 Zn finger	298..318	CDD:275368	2/19 (11%)
		C2H2 Zn finger	326..346	CDD:275368	3/19 (16%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)