DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and prg

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001260253.1 Gene:prg / 34177 FlyBaseID:FBgn0285971 Length:558 Species:Drosophila melanogaster


Alignment Length:592 Identity:119/592 - (20%)
Similarity:190/592 - (32%) Gaps:239/592 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 TSTQKWIVCRVCLQQPKEPMASIFNDDSEKDLTHMIRECGGVPIK---------QFDH---YPDK 67
            |..|....||:|.........:||:|        .::.|..|.|.         |:|.   ..:.
  Fly     9 TQDQDVSTCRLCHHNTDPNSLNIFDD--------TVQFCKDVSIAEVSKSLWSVQYDRNECLSEL 65

  Fly    68 ICEKCFKVLKMAFKFRETCQRSYGHLRQ----------------------FV---GPVEVEQRPP 107
            ||.:|.::|:.||:.|:..|.....|::                      ||   |.:.||..|.
  Fly    66 ICSRCLEILEEAFELRKGMQEREQSLQEQLKEMIKDHPKHRPGLNGNPGVFVPEEGCIIVEVDPE 130

  Fly   108 E-KKGSETATKLEPD-----VDPDEAEQEPEHDEED-------EDVD----LDESHYAEADDAAE 155
            . .:.||....|..|     .|.|:.|:|.::||||       ||||    :|.:..|.....|.
  Fly   131 NLAESSEEEFALGSDGEYENYDDDDEEEEEDYDEEDEEDGQNGEDVDMPLGMDAAQMAAQQSVAN 195

  Fly   156 TQGGVFHDEIEDGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETYEGDLIPDQGYDHEMADQA 220
            ...                       ..|...:...:.:..|:     |..:|.:..:||:|   
  Fly   196 NAN-----------------------TTEARPKRAFLCQYCDL-----GFTLPAECQEHELA--- 229

  Fly   221 LSELSAEIEYLDQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASI-------------HAR 272
                                  ||:.:|....|....:.|...::.:.|             |.|
  Fly   230 ----------------------AHDPNAPYCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCR 272

  Fly   273 NATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLAR 337
            ....||                                   ||       :|....:        
  Fly   273 KGFVRR-----------------------------------SD-------LKKHTIV-------- 287

  Fly   338 KHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQ 402
             |:|::               .:.|:||...:...:.||:|:::||||||..|:.|...|..|.:
  Fly   288 -HTGVR---------------PFTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVE 336

  Fly   403 LARHMNTHTGNRPYKCSYCPAAFADLSTRNK---HHRIHT------------------------- 439
            :.||..:|...:.::|..||.:|   |.|:|   |.::||                         
  Fly   337 MMRHTRSHGEVKAFQCGRCPYSF---SRRDKLIAHQQVHTRRDMEQQQQMGLIPPMEGDLQQQAL 398

  Fly   440 -----------NERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVI 493
                       |.|.|.||||.:||.....|:.|:.:|. :....|..|.:||.:..:|:.|.: 
  Fly   399 QAKQKAAAQTKNSRYYHCDVCDRTFQRERDLQRHQALHM-DSLFACKTCNQGFNRREQLQRHEL- 461

  Fly   494 HERRGQS 500
             |..|.|
  Fly   462 -EAHGPS 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871 20/84 (24%)
C2H2 Zn finger 362..382 CDD:275368 6/19 (32%)
zf-H2C2_2 375..399 CDD:290200 12/23 (52%)
COG5048 386..>447 CDD:227381 22/99 (22%)
C2H2 Zn finger 390..410 CDD:275368 6/19 (32%)
zf-H2C2_2 403..426 CDD:290200 6/22 (27%)
C2H2 Zn finger 418..438 CDD:275368 8/22 (36%)
zf-H2C2_2 432..455 CDD:290200 13/61 (21%)
C2H2 Zn finger 446..466 CDD:275368 8/19 (42%)
zf-H2C2_2 459..481 CDD:290200 5/21 (24%)
C2H2 Zn finger 474..494 CDD:275368 6/19 (32%)
prgNP_001260253.1 zf-AD 16..94 CDD:285071 20/85 (24%)
COG5048 <212..340 CDD:227381 37/223 (17%)
C2H2 Zn finger 239..260 CDD:275368 3/20 (15%)
C2H2 Zn finger 268..288 CDD:275368 7/70 (10%)
zf-H2C2_2 280..305 CDD:290200 7/55 (13%)
zf-C2H2 294..316 CDD:278523 6/21 (29%)
C2H2 Zn finger 296..316 CDD:275368 6/19 (32%)
zf-H2C2_2 308..331 CDD:290200 11/22 (50%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
C2H2 Zn finger 352..372 CDD:275368 8/22 (36%)
C2H2 Zn finger 416..436 CDD:275368 8/19 (42%)
C2H2 Zn finger 443..464 CDD:275368 7/22 (32%)
C2H2 Zn finger 470..490 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457880
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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