DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4936 and ace2

DIOPT Version :9

Sequence 1:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_594109.1	Gene:	ace2 / 2541661	PomBaseID:	SPAC6G10.12c	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	259	Identity:	60/259 - (23%)
Similarity:	97/259 - (37%)	Gaps:	56/259 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 HEMADQALSELSAEIEYLDQVEHDQLTESAHEDDAEVDLNST-EEEFVPSKSVRASIHARNATKR 277
            |....:|.::||:..||:.:.|..........|.:..::|:| .::|..|....:.|    .||:
pombe   308 HTDNQKAFAKLSSPAEYVSEFEKFSSVCDHGLDISNANINNTLTQQFALSAPYESCI----VTKK 368

  Fly   278 -----RVNPRRSATSTASVAVESSTSKTTDRGN--PLKVRRGNSDSAGSKMSIKSEKDISI-GEV 334
                 .|............|..|.|.:.|:..:  |:::    |.....|...:|.:...| .|.
pombe   369 PEPCITVKEEEQLAPKIESADLSITPQVTEHDSKPPVRI----SYDHRCKTRKQSTRICRIPPET 429

  Fly   335 LARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQ 399
            :|..:.|.:..|            ||:|                  :::|        |....|:
pombe   430 MASLYCGPEADG------------KYVC------------------LYNG--------CNKRIAR 456

  Fly   400 AQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHK 463
            ...:..|:.||..:|||:|..|.|.|.......:|.|||.|.|||.|: |.|.|...:.|..||
pombe   457 KYNVESHIQTHLSDRPYRCDLCKAGFVRHHDLKRHLRIHENGRPYVCE-CLKRFNRLDALNRHK 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	1/19 (5%)
		zf-H2C2_2	375..399	CDD:290200	2/23 (9%)
		COG5048	386..>447	CDD:227381	20/60 (33%)
		C2H2 Zn finger	390..410	CDD:275368	3/19 (16%)
		zf-H2C2_2	403..426	CDD:290200	9/22 (41%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		zf-H2C2_2	432..455	CDD:290200	12/22 (55%)
		C2H2 Zn finger	446..466	CDD:275368	7/18 (39%)
		zf-H2C2_2	459..481	CDD:290200	3/5 (60%)
		C2H2 Zn finger	474..494	CDD:275368
ace2	NP_594109.1	COG5048	45..518	CDD:227381	58/256 (23%)
		C2H2 Zn finger	448..467	CDD:275368	4/26 (15%)
		zf-C2H2	473..495	CDD:278523	7/21 (33%)
		C2H2 Zn finger	475..495	CDD:275368	6/19 (32%)
		zf-H2C2_2	487..511	CDD:290200	12/24 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050