DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4936 and Zfp62

DIOPT Version :9

Sequence 1:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001349654.1	Gene:	Zfp62 / 22720	MGIID:	99662	Length:	914	Species:	Mus musculus

Alignment Length:	437	Identity:	124/437 - (28%)
Similarity:	176/437 - (40%)	Gaps:	102/437 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 EDEDVDLDESHYAEADDAAETQ---GGVFH-DEIEDG-------------ILVELEK------DR 177
            |||    :.|...|.|..|::|   .|.|| |.::..             ||.|.:.      |.
Mouse     9 EDE----ESSKKNENDSNADSQCPSVGFFHKDHMQKSKTGDTCDLFPKWKILKEGKSSIREMIDT 69

  Fly   178 IVHVKNEQVEEDGIIEEVYDVYETYEGDLIPDQGYDHE--------------------------M 216
            ..:..|.::|:|.         ||.|....|.....|:                          :
Mouse    70 HTNAANIKLEQDD---------ETSEKSFYPSTNTMHQTIPTEPNCTKQGEHTENINGNVHPAHI 125

  Fly   217 ADQAL---SELSAEIEYLDQ-VEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATKR 277
            ||:.|   .|.....:|..: |:|    :..|..:...:.:.....|..|.|:|  :|.|..|..
Mouse   126 ADKKLHKCDECGKSFKYNSRLVQH----KIMHTGEKRYECDDCRGTFRSSSSLR--VHKRIHTGE 184

  Fly   278 RVNPRRSATSTASVAVESS--TSKTTDRGNPLKVRRGNSDSAGSKMSIKS-----------EKDI 329
            :  |.:......:....||  ..|:|..|.    :....|..|...:..|           ||..
Mouse   185 K--PYKCDECGKAYMSYSSLINHKSTHSGE----KNCKCDECGKSFNYSSVLDQHKRIHTGEKPY 243

  Fly   330 SIGEV--LARKHSGIKTKGGHK-ILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECE 391
            ..||.  ..|..||::.   || |..|:|   .|.||.||..:.:.|.|..|.::|:|.||:||:
Mouse   244 ECGECGKAFRNSSGLRV---HKRIHTGEK---PYECDTCGKTFSNSSGLRVHKRIHTGEKPYECD 302

  Fly   392 ICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYT 456
            .||..|...:.|..|.:.|.|::||||..|..:|...|...:|..|||.|:|||||.|.|.|..:
Mouse   303 ECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNS 367

  Fly   457 NTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHERRGQSARE 503
            :.|..||.|||||||:.||:|||.|..:..|..|:.||.  |:.|.|
Mouse   368 SGLIVHKRIHTGEKPYKCDICGKAFSYSSGLAVHKSIHP--GKKAHE 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		zf-H2C2_2	375..399	CDD:290200	11/23 (48%)
		COG5048	386..>447	CDD:227381	26/60 (43%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	9/22 (41%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		zf-H2C2_2	432..455	CDD:290200	13/22 (59%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		zf-H2C2_2	459..481	CDD:290200	15/21 (71%)
		C2H2 Zn finger	474..494	CDD:275368	8/19 (42%)
Zfp62	NP_001349654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		10/29 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..101		6/29 (21%)
		COG5048	127..542	CDD:227381	99/306 (32%)
		C2H2 Zn finger	133..153	CDD:275368	4/23 (17%)
		C2H2 Zn finger	161..181	CDD:275368	6/21 (29%)
		C2H2 Zn finger	189..209	CDD:275368	3/19 (16%)
		C2H2 Zn finger	217..237	CDD:275368	3/19 (16%)
		C2H2 Zn finger	245..265	CDD:275368	7/22 (32%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)
		C2H2 Zn finger	329..349	CDD:275368	5/19 (26%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		SFP1	<379..458	CDD:227516	17/36 (47%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		C2H2 Zn finger	413..433	CDD:275368	124/437 (28%)
		COG5048	437..850	CDD:227381
		C2H2 Zn finger	441..461	CDD:275368
		C2H2 Zn finger	469..489	CDD:275368
		C2H2 Zn finger	497..517	CDD:275368
		C2H2 Zn finger	525..545	CDD:275368
		C2H2 Zn finger	553..573	CDD:275368
		C2H2 Zn finger	581..601	CDD:275368
		C2H2 Zn finger	609..629	CDD:275368
		C2H2 Zn finger	637..657	CDD:275368
		C2H2 Zn finger	665..685	CDD:275368
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000