DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and Zscan21

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001038168.1 Gene:Zscan21 / 22697 MGIID:99182 Length:555 Species:Mus musculus


Alignment Length:539 Identity:134/539 - (24%)
Similarity:207/539 - (38%) Gaps:133/539 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 PKEPMASIFNDDSEKDLTHMIRECGGVPIK-QFDHYPDKICEKCFKVLKMAFKFRETCQRSYGHL 93
            |:.|..|:                |..||| :.|...||.|              .|.:.|:.|.
Mouse    13 PRPPQESM----------------GPSPIKVEEDEEKDKCC--------------PTLELSHKHF 47

  Fly    94 RQF--------VGPVEVEQRPPEKKGSETATKLEPDVD-----------PDEAEQ-EPEHDEEDE 138
            ||.        :||..::....|.|     .|..|:::           .|..|| .|...:.:|
Mouse    48 RQSGNQDTLEPMGPSTIKAEEDESK-----DKCRPNLEISRKSFKQFGYQDTLEQLGPSTIKAEE 107

  Fly   139 DVDLDESHYAEADDAAETQGGVFHDEIEDGILVELEKDRI---------VHVKNEQVEEDGIIEE 194
            |.:.|:.|.:........:...:||  ..|....|.:.|:         :|.| ||:.|..::|:
Mouse   108 DDEKDKGHPSPEISRQRFRQFGYHD--TPGPREALSQLRVLCCEWLQPEIHTK-EQILELLVLEQ 169

  Fly   195 VYDV----YETYEGDLIPDQGYDH----EMADQALSELSAEIEYLDQVEHDQLTESAHEDDAEVD 251
            ...:    .:|:.....|:...:.    |..:|.|.|...::......:.....:.:....|...
Mouse   170 FLTILPRELQTWVQQHCPESAEEAVTLLEDLEQELDEPGLQVSSPPNEQKQSWEKMSTSGTAMES 234

  Fly   252 LNSTEEEFV---PSKSVRASIHARNATKRRV---NPRRSATSTASVAVESSTSKTTDRGNPLKVR 310
            |:|||.:.|   |.......::.:...:..|   :||:               :...:.||.|  
Mouse   235 LSSTETQHVDASPKYEFWGPLYIQETGEEEVFTQDPRK---------------RQGFKSNPQK-- 282

  Fly   311 RGNSDSAGSKMSIKSE------KDISIGEVLARKH---------SGIKTKGGHKILL---GDKK- 356
               .|||....|.:.|      |...|..:.|.|:         :.::.:.|.|..|   |.:| 
Mouse   283 ---EDSADEHRSSEEESHADGLKRTVIPMIPANKYGSRSERQWANNLERERGTKASLQDTGSRKG 344

  Fly   357 -----------EFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTH 410
                       |.:|||..||..:.:.|.||:|.:.|:|.||:.|..||..|:.:..|..|..||
Mouse   345 AEPASTRPAPGEKRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTH 409

  Fly   411 TGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCD 475
            ..:|||.|. |..||...|...||.|:||.|.||:|..|.|.|:...:|..|..|||||||:.|:
Mouse   410 LVDRPYDCK-CGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCN 473

  Fly   476 VCGKGFPQAYKLRNHRVIH 494
            .|||.|.|...|.:|:.:|
Mouse   474 ECGKSFSQHAGLSSHQRLH 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871 14/65 (22%)
C2H2 Zn finger 362..382 CDD:275368 7/19 (37%)
zf-H2C2_2 375..399 CDD:290200 11/23 (48%)
COG5048 386..>447 CDD:227381 26/60 (43%)
C2H2 Zn finger 390..410 CDD:275368 6/19 (32%)
zf-H2C2_2 403..426 CDD:290200 10/22 (45%)
C2H2 Zn finger 418..438 CDD:275368 8/19 (42%)
zf-H2C2_2 432..455 CDD:290200 12/22 (55%)
C2H2 Zn finger 446..466 CDD:275368 6/19 (32%)
zf-H2C2_2 459..481 CDD:290200 13/21 (62%)
C2H2 Zn finger 474..494 CDD:275368 8/19 (42%)
Zscan21NP_001038168.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..74 20/95 (21%)
3 X 39 AA approximate tandem repeats 18..134 30/152 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 102..133 6/32 (19%)
SCAN 118..230 CDD:128708 17/114 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..243 7/38 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 263..354 20/110 (18%)
COG5048 <339..535 CDD:227381 62/155 (40%)
C2H2 Zn finger 361..381 CDD:275368 7/19 (37%)
C2H2 Zn finger 389..409 CDD:275368 6/19 (32%)
C2H2 Zn finger 419..436 CDD:275368 7/16 (44%)
C2H2 Zn finger 444..464 CDD:275368 6/19 (32%)
C2H2 Zn finger 472..492 CDD:275368 8/19 (42%)
C2H2 Zn finger 500..520 CDD:275368
C2H2 Zn finger 528..548 CDD:275368
zf-C2H2 528..548 CDD:333835
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 151 1.000 Inparanoid score I4340
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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