Protein Alignment CG4936 and klu-2

DIOPT Version :9

• Sequence 1: NP_650862.1
• Gene: CG4936 / 42393
• FlyBaseID: FBgn0038768
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_491843.3
• Gene: klu-2 / 172339
• WormBaseID: WBGene00022592
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 469
• Identity: 100/469 - (21%)
• Similarity: 149/469 - (31%)
• Gaps: 175/469 - (37%)

  Fly    84 ETCQRSYGHLRQFVGPVEVEQRPPEKKGSETATKLEPDVDPDEAEQEPEHD-EEDEDVDLDESHY 147
            :|..|..|....|:|.:   |.||.::...:|....|.|    |.|.|..| .:|||:.:|.:.:
 Worm    29 DTENRGDGESSVFIGQL---QHPPLRRRPVSAMASLPWV----AYQAPREDGTDDEDLAVDSTLF 86

  Fly   148 AEADDAAETQGGV-FHDEIEDGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETYE-------- 203
                  ..|..|: |...:..|           .|.:..:...|:....::....:.
 Worm    87 ------LSTSPGIGFGSSMPGG-----------SVSSLALSPPGLSPLNFNDGSPFSLSSTPSST 134

  Fly   204 GDLIPDQG---YDH---------------EMADQALSELSAEIEYLDQVEHDQLT---ESAHEDD 247
            ..|:.:|.   :||               ......||...|.:    .:||::..   .|.|...
 Worm   135 SSLVRNQNRFTFDHIPFIGSSTNSTPATASTGPPGLSPGGAAL----NIEHEKSAFEIVSCHHQS 195

  Fly   248 AEVDLNSTEEEFVPSKSVRASIHARNATKRRVNPRRS---ATSTASVAVESSTSKTTDRGNPLKV 309
            ||..|.            |..:....:|....|.|.|   ||:|.:.:|| |||.|.|...|
 Worm   196 AEEILQ------------RVRLGTSGSTSSANNLRNSLSEATTTTTGSVE-STSGTADGSAP--- 244

  Fly   310 RRGNSDSAGSKMSIKSEKDISIGEVLARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSR 374
                                  |:                          |.|.:|...:.....
 Worm   245 ----------------------GQ--------------------------YYCFICEKDFRRPDI 261

  Fly   375 LTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYC--PAAFADLSTRN---KH 434
            |:.|.:.|:|.||.:||.||..|:::..|..|..|||..:||.|..|  .|...|:.||:   :|
 Worm   262 LSRHTRRHTGEKPFKCEDCGRFFSRSDHLRTHRRTHTDEKPYHCCVCNYSARRRDVLTRHMSTRH 326

  Fly   435 HRI--------HTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHR 491
            ..|        |.|.|....|.           .:|||                  .|.:||
 Worm   327 QAIAPPSILGTHRNVRRCLSDG-----------DYHKM------------------AAQELR--- 359

  Fly   492 VIHERRGQSARESV 505
                :|.|:.||.|
 Worm   360 ----QRHQATREEV 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871	3/10 (30%)
		C2H2 Zn finger	362..382	CDD:275368	4/19 (21%)
		zf-H2C2_2	375..399	CDD:290200	11/23 (48%)
		COG5048	386..>447	CDD:227381	25/73 (34%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		zf-H2C2_2	403..426	CDD:290200	10/24 (42%)
		C2H2 Zn finger	418..438	CDD:275368	8/32 (25%)
		zf-H2C2_2	432..455	CDD:290200	6/33 (18%)
		C2H2 Zn finger	446..466	CDD:275368	4/19 (21%)
		zf-H2C2_2	459..481	CDD:290200	3/21 (14%)
		C2H2 Zn finger	474..494	CDD:275368	3/19 (16%)
klu-2	NP_491843.3	COG5048	216..>298	CDD:227381	32/133 (24%)
		C2H2 Zn finger	249..269	CDD:275368	4/19 (21%)
		zf-H2C2_2	262..286	CDD:290200	11/23 (48%)
		COG5048	273..>328	CDD:227381	21/54 (39%)
		C2H2 Zn finger	277..297	CDD:275368	7/19 (37%)
		zf-H2C2_2	289..314	CDD:290200	10/24 (42%)
		C2H2 Zn finger	305..324	CDD:275368	6/18 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000