DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and ZNF679

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_699194.2 Gene:ZNF679 / 168417 HGNCID:28650 Length:411 Species:Homo sapiens


Alignment Length:270 Identity:82/270 - (30%)
Similarity:124/270 - (45%) Gaps:50/270 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 EEFVPSKSVRASIHARNATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLKVRRGNSDSAGSKM 321
            ::..|...::.|:       ::|.|||...|    ..::...||.......:|::|..:.....:
Human    95 QDLPPELGIKDSL-------QKVIPRRYGKS----GHDNLQVKTCKSMGECEVQKGGCNEVNQCL 148

  Fly   322 SIKSEKDISIGEVLARKHSGIKTKG------GHKILLGDKKEFK--------------------- 359
            |....|       :.:.|..:|..|      .||.....||.||                     
Human   149 STTQNK-------IFQTHKCVKVFGKFSNSNRHKTRHTGKKHFKCKKYGKSFCMVSQLHQHQIIH 206

  Fly   360 -----YICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCS 419
                 |.|:.||..:...|.|::|.::|:|.||:.||.||..|..:..|.:|...|||.:||.|.
Human   207 TRENSYQCEECGKPFNCSSTLSKHKRIHTGEKPYRCEECGKAFTWSSTLTKHRRIHTGEKPYTCE 271

  Fly   420 YCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQA 484
            .|..||:..||...|.||||.|:||.|:.|.|.|:.:::|.:||.|||||||:.|:.|||.|..:
Human   272 ECGQAFSRSSTLANHKRIHTGEKPYTCEECGKAFSLSSSLTYHKRIHTGEKPYTCEECGKAFNCS 336

  Fly   485 YKLRNHRVIH 494
            ..|:.|::||
Human   337 STLKKHKIIH 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 6/19 (32%)
zf-H2C2_2 375..399 CDD:290200 11/23 (48%)
COG5048 386..>447 CDD:227381 28/60 (47%)
C2H2 Zn finger 390..410 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 10/22 (45%)
C2H2 Zn finger 418..438 CDD:275368 8/19 (42%)
zf-H2C2_2 432..455 CDD:290200 12/22 (55%)
C2H2 Zn finger 446..466 CDD:275368 7/19 (37%)
zf-H2C2_2 459..481 CDD:290200 14/21 (67%)
C2H2 Zn finger 474..494 CDD:275368 7/19 (37%)
ZNF679NP_699194.2 KRAB 16..76 CDD:214630
KRAB 16..55 CDD:279668
C2H2 Zn finger 159..178 CDD:275368 5/18 (28%)
C2H2 Zn finger 186..206 CDD:275368 0/19 (0%)
C2H2 Zn finger 214..234 CDD:275368 6/19 (32%)
zf-H2C2_2 227..250 CDD:290200 10/22 (45%)
COG5048 <238..401 CDD:227381 51/109 (47%)
C2H2 Zn finger 242..262 CDD:275368 7/19 (37%)
zf-H2C2_2 255..279 CDD:290200 11/23 (48%)
C2H2 Zn finger 270..290 CDD:275368 8/19 (42%)
zf-H2C2_2 283..306 CDD:290200 11/22 (50%)
C2H2 Zn finger 298..318 CDD:275368 7/19 (37%)
zf-H2C2_2 310..335 CDD:290200 15/24 (63%)
C2H2 Zn finger 326..346 CDD:275368 7/19 (37%)
zf-H2C2_2 339..362 CDD:290200 4/8 (50%)
C2H2 Zn finger 354..374 CDD:275368
zf-H2C2_2 367..390 CDD:290200
C2H2 Zn finger 382..402 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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