DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and ZNF610

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001154897.1 Gene:ZNF610 / 162963 HGNCID:26687 Length:462 Species:Homo sapiens


Alignment Length:235 Identity:76/235 - (32%)
Similarity:114/235 - (48%) Gaps:22/235 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   269 IHARNATKRRVNPRRSATSTASVAVESSTSKTTDRGN---------PLKVRRGNSDSAGSKMSIK 324
            |:..|..::..|.|.|.:....:    |:|.||...|         ||..:...:...|.....:
Human   145 IYRSNQVEKFTNHRSSVSPLQKI----SSSFTTHIFNKYRNDLIDFPLLPQEEKAYIRGKSYEYE 205

  Fly   325 SEKDISIGEVLARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHE 389
            ..:|   |||...:.|    ...|:::...:|.:|  |..||.::...|.|.||.::|:|.||::
Human   206 CSED---GEVFRVRAS----LTNHQVIHTAEKPYK--CTECGKVFSRNSHLVEHWRIHTGQKPYK 261

  Fly   390 CEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFT 454
            |..|...|.:...||||...|||.:|:||:.|..||.:.|....|..|||.|:||:|:.|.|.|.
Human   262 CSECDKVFNRNSNLARHQRIHTGEKPHKCNECGKAFRECSGLTTHLVIHTGEKPYKCNECGKNFR 326

  Fly   455 YTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIH 494
            :..:|..|:..||.|||:.|:.|||.|.....|..|::||
Human   327 HKFSLTNHQRSHTAEKPYKCNECGKVFSLLSYLARHQIIH 366

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 7/19 (37%)
zf-H2C2_2 375..399 CDD:290200 10/23 (43%)
COG5048 386..>447 CDD:227381 26/60 (43%)
C2H2 Zn finger 390..410 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 12/22 (55%)
C2H2 Zn finger 418..438 CDD:275368 6/19 (32%)
zf-H2C2_2 432..455 CDD:290200 11/22 (50%)
C2H2 Zn finger 446..466 CDD:275368 6/19 (32%)
zf-H2C2_2 459..481 CDD:290200 11/21 (52%)
C2H2 Zn finger 474..494 CDD:275368 7/19 (37%)
ZNF610NP_001154897.1 KRAB 24..82 CDD:214630
KRAB 24..63 CDD:279668
C2H2 Zn finger 206..226 CDD:275368 6/26 (23%)
COG5048 217..>291 CDD:227381 27/79 (34%)
zf-H2C2_2 218..243 CDD:290200 7/30 (23%)
C2H2 Zn finger 234..254 CDD:275368 7/19 (37%)
zf-H2C2_2 246..271 CDD:290200 10/24 (42%)
COG5048 <257..446 CDD:227381 46/110 (42%)
zf-C2H2 260..282 CDD:278523 7/21 (33%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
zf-H2C2_2 274..297 CDD:290200 11/22 (50%)
C2H2 Zn finger 290..310 CDD:275368 6/19 (32%)
zf-H2C2_2 303..327 CDD:290200 11/23 (48%)
zf-C2H2 316..338 CDD:278523 7/21 (33%)
C2H2 Zn finger 318..338 CDD:275368 6/19 (32%)
zf-H2C2_2 330..354 CDD:290200 11/23 (48%)
C2H2 Zn finger 346..366 CDD:275368 7/19 (37%)
zf-H2C2_2 358..382 CDD:290200 4/9 (44%)
C2H2 Zn finger 374..394 CDD:275368
zf-H2C2_2 387..411 CDD:290200
C2H2 Zn finger 402..422 CDD:275368
zf-H2C2_2 414..439 CDD:290200
C2H2 Zn finger 430..450 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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