DRSC/TRiP Functional Genomics Resources

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Protein Alignment idc and ZNF836

DIOPT Version :10

Sequence 1:NP_650862.1 Gene:idc / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001096127.1 Gene:ZNF836 / 162962 HGNCID:34333 Length:936 Species:Homo sapiens


Alignment Length:256 Identity:88/256 - (34%)
Similarity:115/256 - (44%) Gaps:65/256 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   303 RGNPL------KVRRGNSDSAGSKMSIKSEKDISIGE------------VLARKHSGIKT----- 344
            ||.|.      |:.|.|||....:.|...||.....|            :..|.|:|.|.     
Human   270 RGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEKPYKCNE 334

  Fly   345 -----KGG-----HKIL-LGDKKEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFA 398
                 |.|     |:|: .|:|   .|.||:||.::...|.|..|.::|:|.||::|.|||..|:
Human   335 CGKTFKQGSCLTTHQIIHTGEK---PYQCDICGKVFRQNSNLVNHQRIHTGEKPYKCNICGKSFS 396

  Fly   399 QAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCH------------- 450
            |:..||.|...|:||:||||..|...|...|:...|..|||.|:||.||||.             
Human   397 QSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQ 461

  Fly   451 ---------------KTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHER 496
                           |.|:.|:.|..|:.|||||||:.||.|||.|.|...|..|::||.|
Human   462 RSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTR 522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
idcNP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 7/19 (37%)
COG5048 386..>447 CDD:227381 28/60 (47%)
C2H2 Zn finger 390..410 CDD:275368 9/19 (47%)
C2H2 Zn finger 418..438 CDD:275368 5/19 (26%)
SFP1 <424..491 CDD:227516 33/94 (35%)
C2H2 Zn finger 446..466 CDD:275368 9/47 (19%)
C2H2 Zn finger 474..494 CDD:275368 9/19 (47%)
ZNF836NP_001096127.1 KRAB 7..48 CDD:460171
SFP1 <215..297 CDD:227516 9/26 (35%)
C2H2 Zn finger 220..240 CDD:275368
C2H2 Zn finger 248..268 CDD:275368
COG5048 272..648 CDD:227381 86/254 (34%)
C2H2 Zn finger 276..296 CDD:275368 5/19 (26%)
C2H2 Zn finger 304..324 CDD:275368 2/19 (11%)
C2H2 Zn finger 332..352 CDD:275368 4/19 (21%)
C2H2 Zn finger 360..380 CDD:275368 7/19 (37%)
C2H2 Zn finger 388..408 CDD:275368 9/19 (47%)
C2H2 Zn finger 416..436 CDD:275368 5/19 (26%)
C2H2 Zn finger 444..464 CDD:275368 4/19 (21%)
C2H2 Zn finger 472..492 CDD:275368 5/19 (26%)
COG5048 496..904 CDD:227381 14/27 (52%)
C2H2 Zn finger 500..520 CDD:275368 9/19 (47%)
C2H2 Zn finger 528..548 CDD:275368
C2H2 Zn finger 556..576 CDD:275368
C2H2 Zn finger 584..604 CDD:275368
C2H2 Zn finger 612..632 CDD:275368
C2H2 Zn finger 640..660 CDD:275368
C2H2 Zn finger 668..688 CDD:275368
C2H2 Zn finger 696..714 CDD:275370
C2H2 Zn finger 724..744 CDD:275368
C2H2 Zn finger 752..772 CDD:275368
C2H2 Zn finger 780..800 CDD:275368
C2H2 Zn finger 808..828 CDD:275368
C2H2 Zn finger 836..856 CDD:275368
C2H2 Zn finger 864..884 CDD:275368
C2H2 Zn finger 892..912 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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