Protein Alignment idc and ZNF765-ZNF761

DIOPT Version :10

• Sequence 1: NP_650862.1
• Gene: idc / 42393
• FlyBaseID: FBgn0038768
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001337425.1
• Gene: ZNF765-ZNF761 / 110116772
• -ID: -
• Length: 746
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 107/361 - (29%)
• Similarity: 150/361 - (41%)
• Gaps: 68/361 - (18%)

  Fly   178 IVHVKNEQVEE-----DGIIEEVYDVYETYEGDLIPDQGYDHEMADQALSELSAEIEYLDQVEH- 236
            :.|....|:.|     |...::|......||.....|:...||.....:.:|:...|..|| .|
Human    68 VFHAGTLQIHESHHNGDFCYQDVDKDIHDYEFQWQEDERNGHEAPMTKIKKLTGITERYDQ-SHA 131

  Fly   237 ------DQLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATKRRVNPRRSATSTAS-VAVE 294
                  |||..|.|....|:.:..|||:.  ...|..|:|           ..|..|||. ::..
Human   132 RNKPIKDQLGSSFHSHLPEMHIFQTEEKI--DNQVVKSVH-----------DASLVSTAQRISCR 183

  Fly   295 SSTSKTTDRGNPLKVRRGNSDSAGSKMSI-KSEKDISIGEV-LARKHSGIKTKGGHKIL-LGDKK 356
            ..|..:.:.||..    .||.....|..: ..||.....|. .|..:|.:..|  |:|: |.|
Human   184 PKTHISNNHGNNF----WNSSLLTQKQEVHMREKSFQCNESGKAFNYSSLLRK--HQIIHLAD-- 240

  Fly   357 EFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYC 421
              ||.|||||.::..:..|..|.:.|:|..|::|..||..|:|...|..|...|||.:||||..|
Human   241 --KYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEEC 303

  Fly   422 PAA----------------------------FADLSTRNKHHRIHTNERPYECDVCHKTFTYTNT 458
            ..|                            |...|...:|||:||.|:||:|:.|.|||::.::
Human   304 DKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSS 368

  Fly   459 LKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIH 494
            |..|..:||||||:.|:.|||.|.....|..||.:|
Human   369 LTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLH 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
idc	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		COG5048	386..>447	CDD:227381	27/88 (31%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	8/47 (17%)
		SFP1	<424..491	CDD:227516	30/94 (32%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..494	CDD:275368	8/19 (42%)
ZNF765-ZNF761	NP_001337425.1	KRAB	7..48	CDD:460171
		C2H2 Zn finger	217..237	CDD:275368	6/21 (29%)
		COG5048	242..617	CDD:227381	59/163 (36%)
		C2H2 Zn finger	244..264	CDD:275368	7/19 (37%)
		C2H2 Zn finger	272..292	CDD:275368	7/19 (37%)
		C2H2 Zn finger	300..320	CDD:275368	3/19 (16%)
		C2H2 Zn finger	328..348	CDD:275368	5/19 (26%)
		C2H2 Zn finger	356..376	CDD:275368	7/19 (37%)
		C2H2 Zn finger	384..404	CDD:275368	8/19 (42%)
		C2H2 Zn finger	412..432	CDD:275368
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
		C2H2 Zn finger	496..516	CDD:275368
		C2H2 Zn finger	524..544	CDD:275368
		C2H2 Zn finger	552..572	CDD:275368
		C2H2 Zn finger	580..600	CDD:275368
		C2H2 Zn finger	608..628	CDD:275368
		C2H2 Zn finger	636..656	CDD:275368
		zf-H2C2_2	648..673	CDD:463886
		SFP1	<651..737	CDD:227516
		C2H2 Zn finger	664..684	CDD:275368
		C2H2 Zn finger	692..712	CDD:275368
		C2H2 Zn finger	720..740	CDD:275368