DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and E430018J23Rik

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_932128.2 Gene:E430018J23Rik / 101604 MGIID:2141981 Length:461 Species:Mus musculus


Alignment Length:281 Identity:81/281 - (28%)
Similarity:120/281 - (42%) Gaps:55/281 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   245 EDDAEVDLNSTEEEFVPSKSVRASIHAR-NATKRRVNPRRSATSTASVAVESSTSKTTDRGNPLK 308
            |:::||.....:|..|  ...|..:|:. ...|....||....:|..:        .:....|::
Mouse    75 EEESEVWGPGAQEPEV--AMCRTEVHSDCRHEKEGKRPREETKATKKI--------LSPEAGPME 129

  Fly   309 VRRG-NSDSAGSKMSIKSEKDISIGEVLARKHSGIKTKGGHKILLGDKKEFKYICDVCGNMYPSQ 372
            .|.. .|.|...::..|:.:            .|..|...|..:|  |.:.::.|.|||..:..|
Mouse   130 PRPSFASPSCNLELLFKNSQ------------QGHPTVAVHNPIL--KADQRHGCHVCGKSFAHQ 180

  Fly   373 SRLTEHIKVHSGVK----------------------------PHECEICGHCFAQAQQLARHMNT 409
            |:|.||:..|:|.|                            ||:|..||..|.|...|..||.|
Mouse   181 SKLVEHLYTHTGEKPFQCPDCDKYFGRASSLSMHRAIHRGERPHQCPDCGKSFTQRSTLVAHMYT 245

  Fly   410 HTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVC 474
            |||.:|:.|..|..:|:..|:.:.|..||..|||:.|..|.:.||:.:.|..|..:||||||:.|
Mouse   246 HTGEKPFHCPDCNKSFSRPSSLSSHRAIHRGERPHCCSDCGRAFTHRSGLIAHLRVHTGEKPYCC 310

  Fly   475 DVCGKGFPQAYKLRNH-RVIH 494
            ..||:.|.|:..||.| ||:|
Mouse   311 ADCGRCFSQSSGLREHQRVVH 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 9/19 (47%)
zf-H2C2_2 375..399 CDD:290200 12/51 (24%)
COG5048 386..>447 CDD:227381 26/88 (30%)
C2H2 Zn finger 390..410 CDD:275368 8/19 (42%)
zf-H2C2_2 403..426 CDD:290200 10/22 (45%)
C2H2 Zn finger 418..438 CDD:275368 5/19 (26%)
zf-H2C2_2 432..455 CDD:290200 9/22 (41%)
C2H2 Zn finger 446..466 CDD:275368 6/19 (32%)
zf-H2C2_2 459..481 CDD:290200 11/21 (52%)
C2H2 Zn finger 474..494 CDD:275368 10/20 (50%)
E430018J23RikNP_932128.2 KRAB 22..81 CDD:214630 2/5 (40%)
KRAB 22..61 CDD:279668
C2H2 Zn finger 170..190 CDD:275368 9/19 (47%)
zf-H2C2_2 183..207 CDD:290200 6/23 (26%)
C2H2 Zn finger 198..218 CDD:275368 0/19 (0%)
zf-H2C2_2 210..235 CDD:290200 6/24 (25%)
COG5048 <223..383 CDD:227381 48/109 (44%)
C2H2 Zn finger 226..246 CDD:275368 8/19 (42%)
zf-H2C2_2 239..259 CDD:290200 10/19 (53%)
C2H2 Zn finger 254..302 CDD:275368 16/47 (34%)
zf-H2C2_2 298..319 CDD:290200 11/20 (55%)
C2H2 Zn finger 310..331 CDD:275368 10/20 (50%)
C2H2 Zn finger 339..359 CDD:275368
zf-H2C2_2 351..376 CDD:290200
C2H2 Zn finger 367..387 CDD:275368
zf-H2C2_2 383..402 CDD:290200
C2H2 Zn finger 395..415 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 151 1.000 Inparanoid score I4340
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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