DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and ZNF891

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:NP_001264220.1 Gene:ZNF891 / 101060200 HGNCID:38709 Length:544 Species:Homo sapiens


Alignment Length:278 Identity:91/278 - (32%)
Similarity:127/278 - (45%) Gaps:27/278 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   230 YLDQVEHDQLTESAHEDDAEV---DLNST-EEEFVPSKSVRASIHARNATKRRVNPRRSATSTAS 290
            |:.....::|.|| ||.|..:   ..|.| ::|:..||      |..:.| ..:.|..:....|.
Human   235 YVKNSISEKLYES-HECDTTLWHFQRNQTVQKEYTYSK------HGMHFT-HNMFPVPNNLHMAQ 291

  Fly   291 VAVESSTSKTTDRGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLARKHSGIKTKGGHKILLGDK 355
            .|.|.:..:|....:.||       ..|...:.|..:....|:...|..:....|..|   :|:|
Human   292 NACECNKDETLCHQSSLK-------KQGQTHTEKKHECNQCGKAFKRISNLTLYKKSH---MGEK 346

  Fly   356 KEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSY 420
               :|.|..||.::...|.|..|::.|:|.||:||..||..|:|...|..||.||||.:||:|:.
Human   347 ---QYECKECGKVFNDSSTLRRHVRTHTGEKPYECNQCGKAFSQKTSLKAHMRTHTGEKPYECNQ 408

  Fly   421 CPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAY 485
            |..:|...|....|.||||.|:.|||..|.|.|..::.||.||.|||||..:.|..|||.|....
Human   409 CGKSFGTSSYLIVHKRIHTGEKLYECSECGKAFNTSSHLKVHKKIHTGENVYECSDCGKVFSGVS 473

  Fly   486 KLRNHRVIHERRGQSARE 503
            .||.|  |....|:...|
Human   474 SLRMH--IRTHTGEKPYE 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 6/19 (32%)
zf-H2C2_2 375..399 CDD:290200 11/23 (48%)
COG5048 386..>447 CDD:227381 29/60 (48%)
C2H2 Zn finger 390..410 CDD:275368 8/19 (42%)
zf-H2C2_2 403..426 CDD:290200 11/22 (50%)
C2H2 Zn finger 418..438 CDD:275368 6/19 (32%)
zf-H2C2_2 432..455 CDD:290200 12/22 (55%)
C2H2 Zn finger 446..466 CDD:275368 8/19 (42%)
zf-H2C2_2 459..481 CDD:290200 13/21 (62%)
C2H2 Zn finger 474..494 CDD:275368 8/19 (42%)
ZNF891NP_001264220.1 KRAB 43..99 CDD:214630
KRAB 43..82 CDD:279668
COG5048 <272..544 CDD:227381 79/234 (34%)
C2H2 Zn finger 295..315 CDD:275368 5/26 (19%)
C2H2 Zn finger 322..342 CDD:275368 3/19 (16%)
zf-C2H2 348..370 CDD:278523 7/21 (33%)
C2H2 Zn finger 350..370 CDD:275368 6/19 (32%)
zf-H2C2_2 363..387 CDD:290200 11/23 (48%)
C2H2 Zn finger 378..398 CDD:275368 8/19 (42%)
zf-H2C2_2 390..415 CDD:290200 12/24 (50%)
C2H2 Zn finger 406..426 CDD:275368 6/19 (32%)
zf-H2C2_2 418..443 CDD:290200 12/24 (50%)
C2H2 Zn finger 434..454 CDD:275368 8/19 (42%)
zf-H2C2_2 446..470 CDD:290200 13/23 (57%)
C2H2 Zn finger 462..482 CDD:275368 9/21 (43%)
zf-H2C2_2 474..498 CDD:290200 6/18 (33%)
C2H2 Zn finger 490..510 CDD:275368 91/278 (33%)
zf-H2C2_2 502..527 CDD:290200
C2H2 Zn finger 518..538 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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