DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4936 and LOC100362054

DIOPT Version :9

Sequence 1:	NP_650862.1	Gene:	CG4936 / 42393	FlyBaseID:	FBgn0038768	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_038956618.1	Gene:	LOC100362054 / 100362054	RGDID:	2318927	Length:	503	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	87/387 - (22%)
Similarity:	147/387 - (37%)	Gaps:	102/387 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 KDRIVHVKNEQ-----VEED-----GIIEEVYDVYETYEGDLIPDQGYDHEMADQALSELSA--- 226
            |:.|.|::.::     .||:     .|.:::...||..|....|   ::..:.:.:::.:..
  Rat   151 KEVITHLEQQKAAATPTEENVRSLLAIPKDMATGYENTENCQTP---WNASVRNGSVNSIGTMRD 212

  Fly   227 ------EIEYLDQVEHDQLTESAHEDDAEVDLNSTEEEFVPSKSVRASIHARNATKRRVNPRRSA 285
                  .::|.:..|.|.|.|                  :|....|||    ..|.|.......|
  Rat   213 SLLTLQRVQYQEPEEGDVLYE------------------IPQVVRRAS----QGTSRFQERSLRA 255

  Fly   286 TSTASVAVE------SSTSKTTDRGNPLKVRRGNSDSAGSKMSIKSEKDISIGEVLARKHSGIKT 344
            .|:..|.:|      |.|.::.|.|:     ..|:......:|:.:|:| ||..:...::|....
  Rat   256 PSSEDVLMEAKPVFLSLTEQSEDIGD-----GHNTTDVNGGISLTNEED-SIFIIQREQYSEPDM 314

  Fly   345 KGGHKILLGDKKEFKYICDVCG-------NMYPSQSR----------------------LTEHIK 380
            :|   :..|..::.:..  |||       :::.:.|.                      |.::.:
  Rat   315 EG---VSYGVPQDLRIA--VCGTSRSLQESLWAASSEVVPMKVPGFLSRAEQPNPKPVPLFQNYE 374

  Fly   381 VHS-----------GVKPHECEICGHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKH 434
            |:|           ..||::||.|...|.....|:.|..||...||:.|..|...|.:.|....|
  Rat   375 VNSTFEGYQERLQRDPKPYKCEECSRTFKYPCNLSIHQKTHRKERPFFCKECQVGFYEDSELQVH 439

  Fly   435 HRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNH-RVIHE 495
            ..||..|:|:.|..|.|.|.|...|:.|:.|||||||:.|.:|...|.|:.....| |..|:
  Rat   440 EVIHKAEKPFTCSSCGKAFRYKTNLQAHERIHTGEKPYSCSLCNSSFRQSSTYHRHLRKFHK 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4936	NP_650862.1	zf-AD	22..95	CDD:214871
		C2H2 Zn finger	362..382	CDD:275368	5/48 (10%)
		zf-H2C2_2	375..399	CDD:290200	9/34 (26%)
		COG5048	386..>447	CDD:227381	21/60 (35%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		zf-H2C2_2	403..426	CDD:290200	8/22 (36%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		zf-H2C2_2	432..455	CDD:290200	9/22 (41%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		zf-H2C2_2	459..481	CDD:290200	11/21 (52%)
		C2H2 Zn finger	474..494	CDD:275368	6/20 (30%)
LOC100362054	XP_038956618.1	SCAN	40..124	CDD:413396
		zf-C2H2	393..415	CDD:395048	6/21 (29%)
		C2H2 Zn finger	395..415	CDD:275368	6/19 (32%)
		C2H2 Zn finger	423..471	CDD:275368	16/47 (34%)
		C2H2 Zn finger	427..443	CDD:275370	3/15 (20%)
		zf-C2H2	449..471	CDD:395048	7/21 (33%)
		C2H2 Zn finger	479..497	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910