DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4936 and si:dkey-34m19.3

DIOPT Version :9

Sequence 1:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster
Sequence 2:XP_002662346.1 Gene:si:dkey-34m19.3 / 100005466 ZFINID:ZDB-GENE-030131-2206 Length:619 Species:Danio rerio


Alignment Length:494 Identity:128/494 - (25%)
Similarity:189/494 - (38%) Gaps:113/494 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 PVEVEQRPPE---KKGSETATKLEPDVDPDEAEQEPEHDEEDEDVDLDESHYAEADDAAETQGGV 160
            |:|.....|:   ::.|:.|.|..|...||....:|:..|..:.|....|.......|.::....
Zfish   133 PLESSDSLPKSSSRRSSKKAVKQNPPPKPDTPASKPDPLESADSVPSSSSSETSKKAAEQSPPPK 197

  Fly   161 FH------DEIEDGILVELEKDRIVHVK----------NEQVEEDGIIEEVYDVYETYEGDLIPD 209
            .|      |.:|....:.....|....|          :..|.:...:|         ..|.:|.
Zfish   198 PHTPASEPDPLESADSLPKSSSRRSSKKAAKQSPPSKPDTPVTKPDPLE---------SADPLPS 253

  Fly   210 QGYDHEMADQALSELSAEIEYLDQVEHDQLTESAHED--------DAEVDLNSTEEEFVPSKSVR 266
            .. ..|.:.:|:.:......:....|.|.| ||:..|        .|:..|:.::|:.  .|..|
Zfish   254 SS-SGETSKKAVEQSPPPKPHTPATEPDPL-ESSDSDHPYALNPVKAKKKLSESQEQV--DKLRR 314

  Fly   267 ASIHARNATKRRVNPRRSATSTASVAVESSTSKTTDRGNPL----KVRRGNSDS----AGSKMSI 323
            ...:||:..:|:....:|....    ::.....|.:....|    ::..||.:|    ||:|..:
Zfish   315 ELRNARDRERRQKKTMKSLLED----LKKKNMLTEELQEQLNFFSELIGGNDESEEERAGNKPRV 375

  Fly   324 KSEKD---------ISIGEVLARKHSGIKT----------------------KGGHKILL----G 353
            :::|.         ...|:.||..|: :||                      ...||..:    |
Zfish   376 RAKKKKRNRNTFICTECGKTLASIHN-LKTHMMIHTGEKPFPCDQCGKSFRQPSDHKQHMMTHTG 439

  Fly   354 DK-------------------------KEFKYICDVCGNMYPSQSRLTEHIKVHSGVKPHECEIC 393
            :|                         ||..|.|.|||..:...|.|..|.|:|:|||.|.|..|
Zfish   440 EKPYKCNVCDKAFASASNLKLHLRVHTKEKPYSCSVCGKSFSQSSSLKTHQKIHTGVKEHVCLEC 504

  Fly   394 GHCFAQAQQLARHMNTHTGNRPYKCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNT 458
            |..|...|.|.:|...|||.:|||||||...|:.|.....|.||||.|:||||..|.|.|...:.
Zfish   505 GKSFYTGQNLKKHQRIHTGEKPYKCSYCERGFSQLDPMKAHERIHTGEKPYECSHCSKRFNELHN 569

  Fly   459 LKFHKMIHTGEKPHVCDVCGKGFPQAYKLRNHRVIHERR 497
            ||.|:.|||||||:.||:|||.|.|...|:.|...||.:
Zfish   570 LKMHERIHTGEKPYTCDLCGKAFAQLSNLKKHTSAHEEK 608

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4936NP_650862.1 zf-AD 22..95 CDD:214871
C2H2 Zn finger 362..382 CDD:275368 8/19 (42%)
zf-H2C2_2 375..399 CDD:290200 12/23 (52%)
COG5048 386..>447 CDD:227381 30/60 (50%)
C2H2 Zn finger 390..410 CDD:275368 7/19 (37%)
zf-H2C2_2 403..426 CDD:290200 12/22 (55%)
C2H2 Zn finger 418..438 CDD:275368 8/19 (42%)
zf-H2C2_2 432..455 CDD:290200 13/22 (59%)
C2H2 Zn finger 446..466 CDD:275368 7/19 (37%)
zf-H2C2_2 459..481 CDD:290200 15/21 (71%)
C2H2 Zn finger 474..494 CDD:275368 9/19 (47%)
si:dkey-34m19.3XP_002662346.1 THAP 16..96 CDD:283206
C2H2 Zn finger 389..409 CDD:275368 6/20 (30%)
zf-H2C2_2 401..426 CDD:290200 2/25 (8%)
C2H2 Zn finger 417..437 CDD:275368 2/19 (11%)
zf-H2C2_2 431..454 CDD:290200 3/22 (14%)
C2H2 Zn finger 445..465 CDD:275368 0/19 (0%)
zf-H2C2_2 457..482 CDD:290200 7/24 (29%)
C2H2 Zn finger 473..493 CDD:275368 8/19 (42%)
zf-H2C2_2 485..510 CDD:290200 12/24 (50%)
C2H2 Zn finger 501..521 CDD:275368 7/19 (37%)
zf-H2C2_2 513..538 CDD:290200 13/24 (54%)
C2H2 Zn finger 529..549 CDD:275368 8/19 (42%)
zf-H2C2_2 542..565 CDD:290200 12/22 (55%)
C2H2 Zn finger 557..577 CDD:275368 7/19 (37%)
zf-H2C2_2 569..594 CDD:290200 16/24 (67%)
C2H2 Zn finger 585..605 CDD:275368 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170581031
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

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