DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and Zfp869

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001035054.1 Gene:Zfp869 / 66869 MGIID:1914119 Length:529 Species:Mus musculus


Alignment Length:327 Identity:99/327 - (30%)
Similarity:138/327 - (42%) Gaps:60/327 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 EDLSVESVLKSWEDYA-SQ--LDGGMKVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPVPN 170
            |||.|......|:..| ||  |.|.:.:  |..:....:.|..||...:|    ...||...:.|
Mouse    19 EDLVVHFTQDEWDLLAPSQKTLYGDVML--ETFRNFTAVGYEWEDEAIED----HCEDPEVNLRN 77

  Fly   171 EIEEAE-TYAEYEEYELLTNENSPEIAQEKGSTGTDVATEEPPEEEIAEDILDSDEDYDPTHAKP 234
            .:..:| |..|:||||                       |:||:......:...:|  ..|.:.|
Mouse    78 IVTHSEYTQYEHEEYE-----------------------EKPPDSNFLTSVEGLEE--TKTSSGP 117

  Fly   235 EKCDRSGRKPVAYH--------------------KNSPKVETFKKKVGR-KPRNKLST----YIC 274
            ..|:...:....||                    :|..:....:|..|. :..:|:.|    |:|
Mouse   118 SVCEVCLKTFGLYHLTYNGHHNYDYKELRGGHTEENDSEGNQCEKTSGSLQKEDKIHTGKKLYVC 182

  Fly   275 DVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCPAAFAD 339
            ..||..:...:.|..|.:.|:|.||:||:.||:.|.....|..|...|||.:||:|..|..||..
Mouse   183 QECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTY 247

  Fly   340 RSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCDLCGKGFVKAYKLRLHRE 404
            .|....|.||||:|||..|..|.:||.||..||.|:.|||||||:.|..|||.|.....|:||:.
Mouse   248 LSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKR 312

  Fly   405 TH 406
            .|
Mouse   313 IH 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 62/147 (42%)
C2H2 Zn finger 274..294 CDD:275368 5/19 (26%)
zf-H2C2_2 287..311 CDD:290200 11/23 (48%)
C2H2 Zn finger 302..322 CDD:275368 6/19 (32%)
zf-H2C2_2 315..338 CDD:290200 10/22 (45%)
C2H2 Zn finger 330..350 CDD:275368 7/19 (37%)
zf-H2C2_2 345..367 CDD:290200 12/21 (57%)
C2H2 Zn finger 358..378 CDD:275368 9/19 (47%)
zf-H2C2_2 370..394 CDD:290200 14/23 (61%)
C2H2 Zn finger 386..406 CDD:275368 8/19 (42%)
Zfp869NP_001035054.1 KRAB 15..56 CDD:366587 11/38 (29%)
C2H2 Zn finger 158..174 CDD:275368 3/15 (20%)
COG5048 177..510 CDD:227381 60/138 (43%)
C2H2 Zn finger 182..202 CDD:275368 5/19 (26%)
C2H2 Zn finger 210..230 CDD:275368 6/19 (32%)
C2H2 Zn finger 238..258 CDD:275368 7/19 (37%)
C2H2 Zn finger 266..286 CDD:275368 9/19 (47%)
C2H2 Zn finger 294..314 CDD:275368 8/19 (42%)
C2H2 Zn finger 322..342 CDD:275368
C2H2 Zn finger 350..370 CDD:275368
C2H2 Zn finger 378..398 CDD:275368
C2H2 Zn finger 406..426 CDD:275368
C2H2 Zn finger 434..454 CDD:275368
C2H2 Zn finger 462..482 CDD:275368
C2H2 Zn finger 490..510 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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