DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and Zscan25

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001074900.1 Gene:Zscan25 / 666311 MGIID:3647079 Length:543 Species:Mus musculus


Alignment Length:233 Identity:71/233 - (30%)
Similarity:114/233 - (48%) Gaps:25/233 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   197 QEKGSTGTDVATEEPPEEEI-AEDILDSDEDYDPTHAKPEKCDRSGR-----KPVAYHKNSPKVE 255
            ||.||:||.:.....|:..: ..|.|::...:    .||.:|...|:     ..:..|:.:.:.|
Mouse   311 QEPGSSGTSLPGLPAPQHGVPLPDTLNTHNSF----WKPFQCPECGKGFSRSSNLVRHQRTHEEE 371

  Fly   256 ------------TFKKKVGRKPRNKLS--TYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICG 306
                        |.::.:.:..|..|.  .|:|..|...:..:..|..|.:.|:|.||::|..|.
Mouse   372 KSFGCVECGKGFTLREYLTKHQRTHLGKRPYVCGECWKTFSQRHHLEVHQRSHTGEKPYKCSDCW 436

  Fly   307 RGFVQNQQLVRHMNTHTGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNL 371
            :||.:.|.|:.|..||||.:||.|. |..:|:..:....|.|.||.|:||.|.||.:.|:..:.|
Mouse   437 KGFSRRQHLLVHRRTHTGEKPYTCE-CGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGERL 500

  Fly   372 KFHKMIHTGEKPHVCDLCGKGFVKAYKLRLHRETHNRR 409
            ..|:.|||||||:.|..||:.|.:...|..|::|.:|:
Mouse   501 VRHQRIHTGEKPYHCPACGRSFNQRSILNRHQKTQHRQ 538

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 55/148 (37%)
C2H2 Zn finger 274..294 CDD:275368 4/19 (21%)
zf-H2C2_2 287..311 CDD:290200 10/23 (43%)
C2H2 Zn finger 302..322 CDD:275368 7/19 (37%)
zf-H2C2_2 315..338 CDD:290200 10/22 (45%)
C2H2 Zn finger 330..350 CDD:275368 5/19 (26%)
zf-H2C2_2 345..367 CDD:290200 11/21 (52%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
zf-H2C2_2 370..394 CDD:290200 12/23 (52%)
C2H2 Zn finger 386..406 CDD:275368 6/19 (32%)
Zscan25NP_001074900.1 SCAN 38..120 CDD:396558
KRAB_A-box 230..>258 CDD:413388
COG5048 <338..531 CDD:227381 59/197 (30%)
C2H2 Zn finger 348..368 CDD:275368 3/19 (16%)
C2H2 Zn finger 376..396 CDD:275368 2/19 (11%)
C2H2 Zn finger 404..424 CDD:275368 4/19 (21%)
C2H2 Zn finger 432..452 CDD:275368 7/19 (37%)
C2H2 Zn finger 460..479 CDD:275368 5/19 (26%)
C2H2 Zn finger 487..507 CDD:275368 6/19 (32%)
C2H2 Zn finger 515..534 CDD:275368 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 151 1.000 Inparanoid score I4340
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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