DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and OVOL2

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_067043.2 Gene:OVOL2 / 58495 HGNCID:15804 Length:275 Species:Homo sapiens


Alignment Length:233 Identity:71/233 - (30%)
Similarity:98/233 - (42%) Gaps:35/233 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   168 VPNEIEEAETYAEYEEYELLTNENSPEIAQEKGSTGTDVATEEPPEEEIAEDILDSDEDYDPTHA 232
            :|:| :.|:||.......||  .:.||..:..|.:.:...:....|...||   .|...:.|...
Human    22 LPDE-KRADTYIPVGLGRLL--HDPPEDCRSDGGSSSGSGSSSAGEPGGAE---SSSSPHAPESE 80

  Fly   233 KPEKCDRSG--------RKPVAYHKNSPKVETFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTE 289
            .||..|..|        ::|||..|......|....|         .:.||:||..:..|..|..
Human    81 TPEPGDAEGPDGHLATKQRPVARSKIKFTTGTCSDSV---------VHSCDLCGKGFRLQRMLNR 136

  Fly   290 HMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCPAAFADRSTKTKH-HRIH--- 350
            |:|.|:.||.|.|..||:||.....|.||:.||||.||||||.|..||..|.:...| .:||   
Human   137 HLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCNVCNKAFTQRCSLESHLKKIHGVQ 201

  Fly   351 -------TKERPYVCDVCSRTFTYSDNLKFH-KMIHTG 380
                   .:::.|||:.|..|....::|..| ...|.|
Human   202 QQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPG 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 46/129 (36%)
C2H2 Zn finger 274..294 CDD:275368 8/19 (42%)
zf-H2C2_2 287..311 CDD:290200 12/23 (52%)
C2H2 Zn finger 302..322 CDD:275368 8/19 (42%)
zf-H2C2_2 315..338 CDD:290200 15/22 (68%)
C2H2 Zn finger 330..350 CDD:275368 7/20 (35%)
zf-H2C2_2 345..367 CDD:290200 8/32 (25%)
C2H2 Zn finger 358..378 CDD:275368 5/20 (25%)
zf-H2C2_2 370..394 CDD:290200 4/12 (33%)
C2H2 Zn finger 386..406 CDD:275368
OVOL2NP_067043.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 15..101 19/84 (23%)
C2H2 Zn finger 121..141 CDD:275368 8/19 (42%)
C2H2 Zn finger 149..169 CDD:275368 8/19 (42%)
zf-H2C2_2 161..186 CDD:316026 16/24 (67%)
C2H2 Zn finger 177..198 CDD:275368 7/20 (35%)
C2H2 Zn finger 216..233 CDD:275368 4/16 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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