Protein Alignment trem and Zfp213

DIOPT Version :10

• Sequence 1: NP_650861.1
• Gene: trem / 42392
• FlyBaseID: FBgn0038767
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001028668.2
• Gene: Zfp213 / 449521
• MGIID: 3053094
• Length: 468
• Species: Mus musculus
• Alignment Length: 487
• Identity: 116/487 - (23%)
• Similarity: 191/487 - (39%)
• Gaps: 125/487 - (25%)

  Fly    16 LNNPSEGEEL-LHDIFSETASTRLDQMLHICAGIPVSLDDNFPDKMCSKCVRCLRLCYK------ 73
            |.:|:.|||. |..:..|..|...:         ||...|:...:.|.:  |..:.|::
Mouse     7 LQDPAPGEEEGLMIVKVEDCSWEQE---------PVQPVDSRDSEACRQ--RFRQFCFRDAGGPH 60

  Fly    74 ------FRLTCQ------RSHQHIMDMLDREASNANAAGE-------------GDLLSIAEDLSV 113
                  :.|.|:      .|.:.|:::|..|...|...||             .:.:::.||:..
Mouse    61 EAFSQLWELCCRWLRPELHSKEQILELLVLEQFLAVLPGEIQAQLQRQHLGSGEEAVALVEDIQN 125

  Fly   114 ESVLKSW-EDYASQLDGGMKVEG-------------------EEDQQHQVITYVVEDGDTDDT-- 156
            :| ||:| :|..|:.:....|:|                   :..:.|..:. |:::..|.:.
Mouse   126 QS-LKAWPQDELSEAEPKAAVQGLQATGSPQKTGVQKQLPALQGQRSHAQLP-VLKERQTGEVLD 188

  Fly   157 NMFD--VHDPTQPVPNEIE---------EAETYAEYEEYELL-----------TNENSPEIAQEK 199
            ..||  |..|.:|....|.         :...|...||:..|           ..:||.:.|
Mouse   189 GCFDSAVDLPGRPELGRISPFQKSGSLGDIPFYCSREEWSSLDPAQRNLFWNIKRKNSRDAA--- 250

  Fly   200 GSTGTDVATEEPPEEEIAEDILDSDE---DYDPTHAKPEKCD---------------RSGRKPVA 246
              .|....:::||.||.|..:|...|   .::|..|:.|..:               |.||.|.
Mouse   251 --LGLRPKSQKPPAEEAATALLGQTEVPMSWNPEEAETEVWESENPMRTALDPLVGARRGRPPT- 312

  Fly   247 YHKNSPKVETFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQ 311
             |:..     |:..:..||.:      |..||..:...:.|..|.:.|:|.|||:|..|.:.|..
Mouse   313 -HRRQ-----FQNLLAEKPHS------CAQCGKRFRWGSDLARHQRTHTGEKPHKCPECDKSFRS 365

  Fly   312 NQQLVRHMNTHTGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKM 376
            :..||||...|||.:|:.|:.|..:|:..:....|.||||.|:|:.|..|.::|.....|..|:.
Mouse   366 SSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFSCSECGKSFALRSYLLDHRR 430

  Fly   377 IHTGEKPHVCDLCGKGFVKAYKLRLHRETHNR 408
            :||||:|..|..|.|.|.:...|..|:..|::
Mouse   431 VHTGERPFGCGECDKSFKQRAHLIAHQSLHSK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871	18/89 (20%)
		COG5048	<264..411	CDD:227381	50/145 (34%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		C2H2 Zn finger	330..350	CDD:275368	5/19 (26%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
Zfp213	NP_001028668.2	SCAN	41..138	CDD:128708	19/99 (19%)
		KRAB_A-box	214..247	CDD:143639	5/32 (16%)
		COG5048	<324..461	CDD:227381	49/142 (35%)
		C2H2 Zn finger	328..348	CDD:275368	5/19 (26%)
		C2H2 Zn finger	356..376	CDD:275368	7/19 (37%)
		C2H2 Zn finger	384..404	CDD:275368	5/19 (26%)
		C2H2 Zn finger	412..432	CDD:275368	5/19 (26%)
		C2H2 Zn finger	440..460	CDD:275368	6/19 (32%)