DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trem and ovol2

DIOPT Version :9

Sequence 1:	NP_650861.1	Gene:	trem / 42392	FlyBaseID:	FBgn0038767	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001004998.1	Gene:	ovol2 / 448478	XenbaseID:	XB-GENE-854193	Length:	287	Species:	Xenopus tropicalis

Alignment Length:	292	Identity:	79/292 - (27%)
Similarity:	123/292 - (42%)	Gaps:	62/292 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 VPNEIEEAETYA--------EYEEYELLTNE-------NSPE-IAQEKGSTGTDVATEEPPEEEI 216
            :|:| |.|:||.        :|...:.|:|.       :||| .:.:.||....:.|   |....
Frog    22 LPDE-ERADTYIPDTIDCIFKYVTEDSLSNSSAGDPAGDSPERSSSDSGSCNGSITT---PPHNT 82

  Fly   217 AEDILDSDEDYDPTHAKPEK---CDRSGRKPVAYHKNSPKVETFKKKVGRKPRNKLSTYICDVCG 278
            .:..|.|....|.|..:.|:   .|..|::|.|..|......:..:::          |.|::|.
Frog    83 PQSGLVSPSRKDSTKQEDEEEQTSDPHGKRPSARSKIKFTTGSCSEEI----------YSCEICA 137

  Fly   279 NIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCPAAFADRSTK 343
            ..:..|..|..|:|.|:.||.|.|..||:||.....|.||:.||||.|||||..|..||..|.:.
Frog   138 KGFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEICNKAFTQRCSL 202

  Fly   344 TKH-HRIH----------TKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCDLCGKGFVK-- 395
            ..| .:||          .:::.:||:.|..|....::|..|  ::....       |..|:|
Frog   203 ESHLKKIHGVQQGYAYKQRRDKLFVCEDCGYTGPSQEDLYLH--VYDSHP-------GSAFLKKT 258

  Fly   396 AYKLRLHRETHNRRIT----WRNDAEESTKAE 423
            ..||....:|   :||    .::.|:|..:||
Frog   259 TKKLAAILQT---KITSVLQIKSTAQEEVEAE 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871
		COG5048	<264..411	CDD:227381	47/159 (30%)
		C2H2 Zn finger	274..294	CDD:275368	6/19 (32%)
		zf-H2C2_2	287..311	CDD:290200	12/23 (52%)
		C2H2 Zn finger	302..322	CDD:275368	8/19 (42%)
		zf-H2C2_2	315..338	CDD:290200	14/22 (64%)
		C2H2 Zn finger	330..350	CDD:275368	6/20 (30%)
		zf-H2C2_2	345..367	CDD:290200	7/32 (22%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		zf-H2C2_2	370..394	CDD:290200	3/23 (13%)
		C2H2 Zn finger	386..406	CDD:275368	5/21 (24%)
ovol2	NP_001004998.1	C2H2 Zn finger	133..153	CDD:275368	6/19 (32%)
		zf-H2C2_2	145..169	CDD:372612	11/23 (48%)
		C2H2 Zn finger	161..181	CDD:275368	8/19 (42%)
		zf-H2C2_2	173..198	CDD:372612	15/24 (63%)
		zf-C2H2_3rep	189..>250	CDD:376287	14/62 (23%)
		C2H2 Zn finger	189..210	CDD:275368	6/20 (30%)
		C2H2 Zn finger	228..245	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910