DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and CG6654

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster


Alignment Length:584 Identity:128/584 - (21%)
Similarity:202/584 - (34%) Gaps:203/584 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 VCRVCLNNPSEGEELLHDIFSETASTRLDQMLHICAGIPVSLDDNFPDKMCSKCVRCLRLCYKFR 75
            :|..||::...    |..|:...:.:.|..|:..........:||.|:|:|..|:..:..||.|:
  Fly     6 ICLTCLSSTGP----LLSIYDGGSGSCLADMIREFTKTKPRRNDNLPEKVCLSCLSEISNCYTFK 66

  Fly    76 LTCQRSHQHIMDMLDREASNANAAGEGDLLSIA-----EDLSVESVLKSWE----DYASQLDGGM 131
            :.|:.|.:.:..:|    .||........:||:     .|.:|::.  |||    ..:.|.|...
  Fly    67 IKCENSSRTLRQLL----PNALPEEPDSKVSISCPVATTDQAVQTT--SWEPDRCTASVQTDAVT 125

  Fly   132 KVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPV----------------PNEIEEAETYAE 180
            ..:.|::......|..|:.....:..:||...|.:||                ..|:...:|...
  Fly   126 TTDAEQNTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVI 190

  Fly   181 YE--EYEL--------------LTNE------NSPEIA-----------QEKGSTGTDVATEEPP 212
            ||  ::||              :.||      .:|::.           ||.....|.|.::|..
  Fly   191 YEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKHQTPVGSKEEA 255

  Fly   213 EEEIAEDILDS-----------DEDY---DPTHAKPE---------------------------- 235
            .|...|.:..|           .:|.   .|:.|:|.                            
  Fly   256 RELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPSTTSG 320

  Fly   236 ---------KCDRSG-----RKPVAYHK-----------------------------------NS 251
                     .|||..     .|.:..|:                                   |.
  Fly   321 AATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQASHGAHNC 385

  Fly   252 PKV-------ETFKKKV----GRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEIC 305
            |:.       |...|.:    .|..||:     |::|..::...:.|.:||:.|:|.||..|.||
  Fly   386 PECGIRCDSKEALSKHMVQGHKRNLRNQ-----CNICQKVFTMLSTLRDHMRIHTGEKPFVCNIC 445

  Fly   306 GRGFVQN----------------------------QQLVRHMNTHTGNRPYKCNYCPAAFADRST 342
            |:.|.||                            .:|..|..||||::|::|..|.|.|....:
  Fly   446 GKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCS 510

  Fly   343 KTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCDLCGKGFVKAYKLRLHRETH 406
            ..||.|.||.||||.||:|...||..:.||.|:..||||:|:||..|.|.|.:....::|:.||
  Fly   511 LAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTH 574

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871 18/75 (24%)
COG5048 <264..411 CDD:227381 59/171 (35%)
C2H2 Zn finger 274..294 CDD:275368 5/19 (26%)
zf-H2C2_2 287..311 CDD:290200 12/23 (52%)
C2H2 Zn finger 302..322 CDD:275368 9/47 (19%)
zf-H2C2_2 315..338 CDD:290200 10/22 (45%)
C2H2 Zn finger 330..350 CDD:275368 7/19 (37%)
zf-H2C2_2 345..367 CDD:290200 13/21 (62%)
C2H2 Zn finger 358..378 CDD:275368 8/19 (42%)
zf-H2C2_2 370..394 CDD:290200 12/23 (52%)
C2H2 Zn finger 386..406 CDD:275368 5/19 (26%)
CG6654NP_650429.1 zf-AD 6..79 CDD:285071 18/76 (24%)
C2H2 Zn finger 331..354 CDD:275368 5/22 (23%)
COG5048 <357..570 CDD:227381 61/217 (28%)
C2H2 Zn finger 360..380 CDD:275368 0/19 (0%)
C2H2 Zn finger 385..406 CDD:275370 3/20 (15%)
C2H2 Zn finger 414..434 CDD:275368 5/19 (26%)
zf-H2C2_2 427..451 CDD:290200 12/23 (52%)
C2H2 Zn finger 442..490 CDD:275368 9/47 (19%)
C2H2 Zn finger 470..487 CDD:275368 1/16 (6%)
zf-H2C2_2 482..507 CDD:290200 11/24 (46%)
C2H2 Zn finger 498..518 CDD:275368 7/19 (37%)
zf-H2C2_2 510..534 CDD:290200 12/23 (52%)
C2H2 Zn finger 526..546 CDD:275368 8/19 (42%)
zf-H2C2_2 539..563 CDD:290200 13/23 (57%)
C2H2 Zn finger 554..574 CDD:275368 5/19 (26%)
C2H2 Zn finger 582..602 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 84 1.000 Inparanoid score I1804
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.960

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