DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trem and Ovol3

DIOPT Version :9

Sequence 1:	NP_650861.1	Gene:	trem / 42392	FlyBaseID:	FBgn0038767	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001276746.1	Gene:	Ovol3 / 381867	MGIID:	2388075	Length:	189	Species:	Mus musculus

Alignment Length:	184	Identity:	55/184 - (29%)
Similarity:	80/184 - (43%)	Gaps:	25/184 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 EPPEEEIAEDILDSDEDYDPTHAKPEKCDRSGRKPVAYHKNSPKVETF----KKKVGRKPRNKLS 270
            :||......|.|..|. |.|      .|......|.  |::|...:|:    :..:...|:.. .
Mouse    13 QPPNWSHLPDQLRGDA-YVP------DCSSLAVPPA--HRSSGLRDTWAVSSQGTLTSAPKGP-G 67

  Fly   271 TYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCPA 335
            |..|.:|...:|.|..||.|:|.||..:.|.|..||:||.....|.|||.||||.||::|..|..
Mouse    68 TLGCPLCPKAFPLQRMLTRHLKCHSPARRHVCHYCGKGFHDAFDLKRHMRTHTGIRPFRCGACGK 132

  Fly   336 AFADRSTKTKH-HRIH----------TKERPYVCDVCSRTFTYSDNLKFHKMIH 378
            ||..|.:...| .::|          .:|:.:||:.|..|.:..|....|:.:|
Mouse   133 AFTQRCSLEAHLAKVHGQPASYAYRERREKLHVCEDCGFTSSRPDAYAQHRTLH 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871
		COG5048	<264..411	CDD:227381	43/126 (34%)
		C2H2 Zn finger	274..294	CDD:275368	8/19 (42%)
		zf-H2C2_2	287..311	CDD:290200	12/23 (52%)
		C2H2 Zn finger	302..322	CDD:275368	9/19 (47%)
		zf-H2C2_2	315..338	CDD:290200	13/22 (59%)
		C2H2 Zn finger	330..350	CDD:275368	6/20 (30%)
		zf-H2C2_2	345..367	CDD:290200	7/32 (22%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		zf-H2C2_2	370..394	CDD:290200	2/9 (22%)
		C2H2 Zn finger	386..406	CDD:275368
Ovol3	NP_001276746.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		2/6 (33%)
		C2H2 Zn finger	71..91	CDD:275368	8/19 (42%)
		zf-C2H2	97..119	CDD:395048	10/21 (48%)
		C2H2 Zn finger	99..119	CDD:275368	9/19 (47%)
		zf-H2C2_2	111..136	CDD:404364	14/24 (58%)
		C2H2 Zn finger	127..148	CDD:275368	6/20 (30%)
		C2H2 Zn finger	166..186	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910