DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trem and CG32772

DIOPT Version :9

Sequence 1:	NP_650861.1	Gene:	trem / 42392	FlyBaseID:	FBgn0038767	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	86/375 - (22%)
Similarity:	140/375 - (37%)	Gaps:	88/375 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 DKMCSKCVRCLRLCYK----FRL------TCQRSHQHIMDMLDREASNANAAGEGDLLSIAEDLS 112
            |.:|       |||::    |::      ||.|..:.:.:..:...|.|.||......|.|...|
  Fly     2 DTIC-------RLCFQTATLFQVPGYSIPTCVRCSEQLTNNSNFHQSAAAAAAVAASASAAVAAS 59

  Fly   113 VESVLKSWEDYASQLDGGMKVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPVPNEIEEAET 177
            ..:...| ...||..|.....   :.||||                    :|.|.
  Fly    60 AAAAATS-SSTASSSDSDAIA---QQQQHQ--------------------NPQQQ---------- 90

  Fly   178 YAEYEEYELLTNENSPEIAQEKGSTGTDVATEEPPEEEIAEDI--LDSDEDYDPTHAKPEKCDR- 239
                      .::||.:..|::....:..::|....::.:||:  :.::|...|.      |::
  Fly    91 ----------QHQNSQQQQQQQQQMQSSSSSENLQSQDDSEDVDLIFNEEGSCPL------CNKT 139

  Fly   240 -SGRKPVAYHKNSPKVETFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECE 303
             |.:..:..|..:...|       ||       ::|..|...:...|.|..|.:.|:..:|::|.
  Fly   140 FSRKSSLMTHIRNHSAE-------RK-------FVCTYCHKGFTQAANLRNHERIHTNDRPYQCV 190

  Fly   304 ICGRGFVQNQQLVRHMNTHTGNRPYKCN--YCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFT 366
            .||:.|.|...|..|...|||.||:.||  .|..:||..:....|.:.|.|.:.|.|:||::.||
  Fly   191 DCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFT 255

  Fly   367 YSDNLKFHKMIHTGEKPHVCDLC-GKGFVKAYKLRLHRETHNRRITWRND 415
            ...:|..|...|.|...:.|..| .|.|....:|..|.:||.....:..|
  Fly   256 QVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECD 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871	9/38 (24%)
		COG5048	<264..411	CDD:227381	46/149 (31%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		zf-H2C2_2	287..311	CDD:290200	8/23 (35%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		zf-H2C2_2	315..338	CDD:290200	10/24 (42%)
		C2H2 Zn finger	330..350	CDD:275368	6/21 (29%)
		zf-H2C2_2	345..367	CDD:290200	8/21 (38%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		zf-H2C2_2	370..394	CDD:290200	7/24 (29%)
		C2H2 Zn finger	386..406	CDD:275368	6/20 (30%)
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	54/202 (27%)
		C2H2 Zn finger	133..153	CDD:275368	4/25 (16%)
		zf-H2C2_2	145..170	CDD:290200	6/38 (16%)
		C2H2 Zn finger	161..181	CDD:275368	5/19 (26%)
		zf-H2C2_2	173..198	CDD:290200	8/24 (33%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..239	CDD:275368	6/21 (29%)
		zf-H2C2_2	231..256	CDD:290200	8/24 (33%)
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		C2H2 Zn finger	275..296	CDD:275368	6/20 (30%)
		C2H2 Zn finger	304..324	CDD:275368	1/2 (50%)
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010