DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and ZNF707

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001094068.1 Gene:ZNF707 / 286075 HGNCID:27815 Length:371 Species:Homo sapiens


Alignment Length:222 Identity:69/222 - (31%)
Similarity:96/222 - (43%) Gaps:45/222 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   221 LDSDEDYDPTHAKPEKCDRSGRKPVAYHKNSPKVETFKKKVGRKP----RNKLS----TYICDVC 277
            ||:|:...| .|.||:.|   .||.|:     ..:...::.||:|    |.|..    ::||..|
Human   126 LDTDDGQLP-RAAPERTD---AKPTAF-----PCQVLTQRCGRRPGRRERRKQRAVELSFICGTC 181

  Fly   278 GNIYPTQARLTEHMKFHSGVKPHE----------------------------CEICGRGFVQNQQ 314
            |......:||..|...|:|.|..|                            ||.||:.|....:
Human   182 GKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACGQAFSLKDR 246

  Fly   315 LVRHMNTHTGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHT 379
            |.:|...||.:|||.|..|..||..:|...:|..:||.|||:.|..|.:.|...:||..|:.:|:
Human   247 LAQHRKVHTEHRPYSCGDCGKAFKQKSNLLRHQLVHTGERPFYCADCGKAFRTKENLSHHQRVHS 311

  Fly   380 GEKPHVCDLCGKGFVKAYKLRLHRETH 406
            ||||:.|..|||.|.......:||..|
Human   312 GEKPYTCAECGKSFRWPKGFSIHRRLH 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 56/179 (31%)
C2H2 Zn finger 274..294 CDD:275368 6/19 (32%)
zf-H2C2_2 287..311 CDD:290200 11/51 (22%)
C2H2 Zn finger 302..322 CDD:275368 7/19 (37%)
zf-H2C2_2 315..338 CDD:290200 10/22 (45%)
C2H2 Zn finger 330..350 CDD:275368 6/19 (32%)
zf-H2C2_2 345..367 CDD:290200 9/21 (43%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
zf-H2C2_2 370..394 CDD:290200 12/23 (52%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
ZNF707NP_001094068.1 KRAB 8..68 CDD:214630
KRAB 8..47 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..143 8/20 (40%)
C2H2 Zn finger 178..198 CDD:275368 6/19 (32%)
COG5048 <187..366 CDD:227381 49/152 (32%)
C2H2 Zn finger 206..226 CDD:275368 0/19 (0%)
zf-H2C2_2 218..242 CDD:290200 4/23 (17%)
C2H2 Zn finger 234..254 CDD:275368 7/19 (37%)
zf-C2H2 260..282 CDD:278523 7/21 (33%)
C2H2 Zn finger 262..282 CDD:275368 6/19 (32%)
zf-H2C2_2 274..299 CDD:290200 9/24 (38%)
C2H2 Zn finger 290..310 CDD:275368 6/19 (32%)
zf-H2C2_2 302..325 CDD:290200 12/22 (55%)
C2H2 Zn finger 318..338 CDD:275368 7/19 (37%)
C2H2 Zn finger 346..366 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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