DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and 5730507C01Rik

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001188259.1 Gene:5730507C01Rik / 236366 MGIID:1917882 Length:416 Species:Mus musculus


Alignment Length:355 Identity:95/355 - (26%)
Similarity:140/355 - (39%) Gaps:67/355 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 QLDGGMKVEGEEDQQHQVITYVVEDGDTDDTNMFDVH-----------DPTQPVPNEIEEAETY- 178
            ::.|.:...|:|.   .|....:..|..|.....|||           ||:|....:....||| 
Mouse    42 EVSGSVARAGQET---SVAGIALRPGHPDAVTYDDVHVNFTGEEWNLLDPSQKSLYKDVMLETYW 103

  Fly   179 ------AEYEEY------------ELLTNENSPEIAQEKGSTGTDVATEEPPEEEIAEDILDSDE 225
                  ..:|.:            |...:.:|.|...|........:.....:..|...|.:...
Mouse   104 NLAVIGYTWENHHIERHCQSSRRNERYVSNHSGEKLYECNERSKAFSCPSHLQSNIRRQIGEKIH 168

  Fly   226 DYD--------PTHAKPEKCDRSGRKPVAYHKNSPKVETFKK----KVGRKPRNKLSTYICDVCG 278
            :::        |:|.:..|...:|.||...|:..   :.|||    :..::......:|.|:.||
Mouse   169 EHNQCCKAFPTPSHLQYHKRIHTGEKPYECHQCG---QDFKKCSHLQCHKRTHTGEKSYECNQCG 230

  Fly   279 NIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCPAAFADRSTK 343
            ..:.....|..|.:.|:|.||:||..||:.|.:...|..|..||||.:||:||.|..||:..|..
Mouse   231 KPFAQLGSLNRHKRTHTGEKPYECHQCGKAFARLSSLHCHKRTHTGEKPYECNQCGKAFSQPSHL 295

  Fly   344 TKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCDLCGKGFVKAYKLRLHRETHNR 408
            ..|.|.||.|:||.|:.|.:.|....||:.||..||||||:.|:.|||.|.....|:.|:.||. 
Mouse   296 QSHKRTHTGEKPYECNQCGKAFAELSNLQRHKRTHTGEKPYECNQCGKAFAGHNVLQSHQRTHT- 359

  Fly   409 RITWRNDAEESTKAEDVKGETPEFLNELPK 438
                              ||.|...|:..|
Mouse   360 ------------------GEKPYECNQCGK 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 58/146 (40%)
C2H2 Zn finger 274..294 CDD:275368 5/19 (26%)
zf-H2C2_2 287..311 CDD:290200 11/23 (48%)
C2H2 Zn finger 302..322 CDD:275368 6/19 (32%)
zf-H2C2_2 315..338 CDD:290200 12/22 (55%)
C2H2 Zn finger 330..350 CDD:275368 8/19 (42%)
zf-H2C2_2 345..367 CDD:290200 10/21 (48%)
C2H2 Zn finger 358..378 CDD:275368 7/19 (37%)
zf-H2C2_2 370..394 CDD:290200 14/23 (61%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
5730507C01RikNP_001188259.1 KRAB 69..>110 CDD:214630 9/40 (23%)
KRAB 69..106 CDD:279668 9/36 (25%)
COG5048 <119..293 CDD:227381 44/176 (25%)
C2H2 Zn finger 142..162 CDD:275368 1/19 (5%)
C2H2 Zn finger 171..190 CDD:275368 3/18 (17%)
zf-H2C2_2 182..206 CDD:290200 6/26 (23%)
C2H2 Zn finger 198..218 CDD:275368 4/22 (18%)
zf-H2C2_2 210..235 CDD:290200 4/24 (17%)
COG5048 <222..374 CDD:227381 63/169 (37%)
C2H2 Zn finger 226..246 CDD:275368 5/19 (26%)
zf-H2C2_2 238..263 CDD:290200 11/24 (46%)
C2H2 Zn finger 254..274 CDD:275368 6/19 (32%)
zf-H2C2_2 270..291 CDD:290200 12/20 (60%)
C2H2 Zn finger 282..302 CDD:275368 8/19 (42%)
zf-H2C2_2 294..318 CDD:290200 9/23 (39%)
C2H2 Zn finger 310..330 CDD:275368 7/19 (37%)
zf-H2C2_2 322..346 CDD:290200 14/23 (61%)
C2H2 Zn finger 338..358 CDD:275368 7/19 (37%)
zf-H2C2_2 351..374 CDD:290200 9/40 (23%)
C2H2 Zn finger 366..386 CDD:275368 2/6 (33%)
C2H2 Zn finger 393..414 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 151 1.000 Inparanoid score I4340
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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