DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment trem and Ovol1

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_064319.1 Gene:Ovol1 / 18426 MGIID:1330290 Length:267 Species:Mus musculus


Alignment Length:204 Identity:65/204 - (31%)
Similarity:86/204 - (42%) Gaps:42/204 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   205 DVATEEPPEEEIAEDILDSDEDYDPTHAKPEKC--------DRSGRKPVAYHKNSPKVE------ 255
            :.:..|||...:|.|:...|..|.   ..|..|        |.|       |...|:..      
Mouse    48 EASVAEPPSCPLALDMSLRDSSYS---VAPGPCVVAQLPSEDVS-------HLTDPQSRDQGFLR 102

  Fly   256 -TFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHM 319
             ..|..:|..|...|.|  |.:|...:..|..|..|||.|:.||.|.|..||:||.....|.||:
Mouse   103 TKMKVTLGDSPNGDLFT--CHICQKSFTHQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHV 165

  Fly   320 NTHTGNRPYKCNYCPAAFADRSTKTKH-HRIH-------TKERP---YVCDVCSRTFTYSDNLKF 373
            .||||.|||||:.|..||..|.:...| .:||       .|||.   |||:.|..|   |::.:.
Mouse   166 RTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCT---SESQEG 227

  Fly   374 HKMIHTGEK 382
            | ::|..|:
Mouse   228 H-VLHLKER 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 50/130 (38%)
C2H2 Zn finger 274..294 CDD:275368 7/19 (37%)
zf-H2C2_2 287..311 CDD:290200 13/23 (57%)
C2H2 Zn finger 302..322 CDD:275368 8/19 (42%)
zf-H2C2_2 315..338 CDD:290200 14/22 (64%)
C2H2 Zn finger 330..350 CDD:275368 6/20 (30%)
zf-H2C2_2 345..367 CDD:290200 11/32 (34%)
C2H2 Zn finger 358..378 CDD:275368 5/19 (26%)
zf-H2C2_2 370..394 CDD:290200 3/13 (23%)
C2H2 Zn finger 386..406 CDD:275368
Ovol1NP_064319.1 zf-C2H2 118..138 CDD:333835 6/21 (29%)
C2H2 Zn finger 120..140 CDD:275368 7/19 (37%)
C2H2 Zn finger 148..168 CDD:275368 8/19 (42%)
zf-H2C2_2 160..185 CDD:372612 15/24 (63%)
C2H2 Zn finger 176..197 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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