DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trem and C04F5.9

DIOPT Version :9

Sequence 1:	NP_650861.1	Gene:	trem / 42392	FlyBaseID:	FBgn0038767	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_504371.1	Gene:	C04F5.9 / 178899	WormBaseID:	WBGene00015451	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	185	Identity:	46/185 - (24%)
Similarity:	56/185 - (30%)	Gaps:	74/185 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 KPHECEICGRGFVQNQQLVRHMNTH--TGNRPYKCNYCPAAFADRSTKTKHHRIH-TKERPYVCD 359
            |.|.|..|...|....:|.||:.||  ||. .:.|..|...|...|:.|.|.|.. .|.:...||
Worm     3 KDHRCPQCLLEFPFASKLQRHLETHLITGG-DWLCGLCDTLFNRSSSLTNHWRNSCAKVKMAFCD 66

  Fly   360 ----------------------------------VCSRTFTYSDN----------------LKFH 374
                                              ..|...|.||:                |..|
Worm    67 DELKEMLVYDLREAVFRMTLDHYSASEKSPEEPGTSSSYKTASDDKTSICIYCNLLMPRGTLHHH 131

  Fly   375 KMIHTGE-----------KPHVCDLCGKGFVKAYKLRLHRETHNRRITWRNDAEE 418
            ..:|||.           .|:||||||.||  .||..|:..       ||:...|
Worm   132 YSVHTGRCCPAEITQNSVVPYVCDLCGFGF--RYKKSLYNH-------WRHKCTE 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871
		COG5048	<264..411	CDD:227381	43/176 (24%)
		C2H2 Zn finger	274..294	CDD:275368
		zf-H2C2_2	287..311	CDD:290200	5/12 (42%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		zf-H2C2_2	315..338	CDD:290200	9/24 (38%)
		C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)
		zf-H2C2_2	345..367	CDD:290200	6/56 (11%)
		C2H2 Zn finger	358..378	CDD:275368	8/69 (12%)
		zf-H2C2_2	370..394	CDD:290200	13/50 (26%)
		C2H2 Zn finger	386..406	CDD:275368	10/19 (53%)
C04F5.9	NP_504371.1	C2H2 Zn finger	7..27	CDD:275368	6/19 (32%)
C04F5.9	NP_504371.1	C2H2 Zn finger	36..54	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000