DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trem and M03D4.4

DIOPT Version :9

Sequence 1:	NP_650861.1	Gene:	trem / 42392	FlyBaseID:	FBgn0038767	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	70/271 - (25%)
Similarity:	109/271 - (40%)	Gaps:	72/271 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 KVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPVPNEIEEAETYAEYEEYELLTNENSPEIA 196
            :::..|.::|:    .||.||.::..|.|..|....:..:||:::..::.:..:|..|..:|
Worm    19 ELQRHEREEHE----TVEQGDQEEDRMEDDSDELAMIKIKIEDSDFLSDTDSSQLSMNPTTP--- 76

  Fly   197 QEKGSTGTDVATEEPPEEEIAEDILDSDEDYDPTHAKPEKCDRSGRKPVAYHKNSPKVETFKKKV 261
            .||.|:|                               ||
Worm    77 SEKSSSG-------------------------------EK------------------------- 85

  Fly   262 GRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNR 326
            ||        |.|:.|..::..:..|..||:.|||.:||.|..||:.|...|.|.:|...|||.|
Worm    86 GR--------YECEDCHEMFAVKRELATHMRIHSGEQPHSCTQCGKEFGTRQLLKKHWMWHTGER 142

  Fly   327 PYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCDLCGK 391
            .:.|.:|..||..:...|:|..||:..||:.|..|.:||.:..:|..|..||. |:...|..||:
Worm   143 SHVCPHCNKAFFQKGHLTQHLMIHSGGRPHECPQCHKTFIFKFDLNRHMKIHQ-ERGFSCQQCGR 206

  Fly   392 GFVKAYKLRLH 402
            .|:|...|..|
Worm   207 SFLKQVMLDEH 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871
		COG5048	<264..411	CDD:227381	48/139 (35%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		zf-H2C2_2	287..311	CDD:290200	12/23 (52%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		zf-H2C2_2	315..338	CDD:290200	9/22 (41%)
		C2H2 Zn finger	330..350	CDD:275368	6/19 (32%)
		zf-H2C2_2	345..367	CDD:290200	9/21 (43%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
		zf-H2C2_2	370..394	CDD:290200	8/23 (35%)
		C2H2 Zn finger	386..406	CDD:275368	7/17 (41%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	5/19 (26%)
		zf-H2C2_2	102..127	CDD:290200	12/24 (50%)
		C2H2 Zn finger	118..138	CDD:275368	7/19 (37%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	158..181	CDD:290200	8/22 (36%)
		zf-C2H2	172..194	CDD:278523	6/21 (29%)
		C2H2 Zn finger	174..194	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000