DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and ZNF785

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:XP_011544054.1 Gene:ZNF785 / 146540 HGNCID:26496 Length:418 Species:Homo sapiens


Alignment Length:280 Identity:85/280 - (30%)
Similarity:120/280 - (42%) Gaps:56/280 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 PVPNEIE--EAETYAEYEEYELLTNENSPEIAQEKG-STGTDVATEE-------PPEEEIAEDIL 221
            |.|..|.  |.|..|...|.:....|:|...::.:| ..|:....||       |.::|:|.:: 
Human    86 PKPAFISWVEGEVEAWSPEAQDPDGESSAAFSRGQGQEAGSRDGNEEKERLKKCPKQKEVAHEV- 149

  Fly   222 DSDEDYDPTHAKPEKCDRSGRKPVAYHKNSPKVETFKKKVGRK-PRNKLSTYICDVCGN--IYPT 283
             :.:::.|:.|.||.|:         .:.||.....|..:.|: |.:      |..||.  .||:
Human   150 -AVKEWWPSVACPEFCN---------PRQSPMNPWLKDTLTRRLPHS------CPDCGRNFSYPS 198

  Fly   284 --------------------QAR------LTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTH 322
                                |||      |.:|...|:|.||:.|..|||.|.|...|..|...|
Human   199 LLASHQRVHSGERPFSCGQCQARFSQRRYLLQHQFIHTGEKPYPCPDCGRRFRQRGSLAIHRRAH 263

  Fly   323 TGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCD 387
            ||.:||.|:.|.:.|........|.|.||.|:||.|..||..|.|:..|..|:.|||||||:.|.
Human   264 TGEKPYACSDCKSRFTYPYLLAIHQRKHTGEKPYSCPDCSLRFAYTSLLAIHRRIHTGEKPYPCP 328

  Fly   388 LCGKGFVKAYKLRLHRETHN 407
            .||:.|..:..|..||..|:
Human   329 DCGRRFTYSSLLLSHRRIHS 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 60/173 (35%)
C2H2 Zn finger 274..294 CDD:275368 10/47 (21%)
zf-H2C2_2 287..311 CDD:290200 11/23 (48%)
C2H2 Zn finger 302..322 CDD:275368 8/19 (42%)
zf-H2C2_2 315..338 CDD:290200 9/22 (41%)
C2H2 Zn finger 330..350 CDD:275368 5/19 (26%)
zf-H2C2_2 345..367 CDD:290200 11/21 (52%)
C2H2 Zn finger 358..378 CDD:275368 7/19 (37%)
zf-H2C2_2 370..394 CDD:290200 12/23 (52%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
ZNF785XP_011544054.1 KRAB 29..102 CDD:214630 6/15 (40%)
COG5048 <156..372 CDD:227381 69/208 (33%)
C2H2 Zn finger 187..207 CDD:275368 5/19 (26%)
C2H2 Zn finger 215..235 CDD:275368 5/19 (26%)
C2H2 Zn finger 243..263 CDD:275368 8/19 (42%)
C2H2 Zn finger 271..291 CDD:275368 5/19 (26%)
C2H2 Zn finger 299..319 CDD:275368 7/19 (37%)
C2H2 Zn finger 327..347 CDD:275368 7/19 (37%)
C2H2 Zn finger 355..375 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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