Protein Alignment trem and ZSCAN29

DIOPT Version :9

• Sequence 1: NP_650861.1
• Gene: trem / 42392
• FlyBaseID: FBgn0038767
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001359009.1
• Gene: ZSCAN29 / 146050
• HGNCID: 26673
• Length: 852
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 93/347 - (26%)
• Similarity: 133/347 - (38%)
• Gaps: 97/347 - (27%)

  Fly   148 VEDGDTDDTNMF-----------------DVHDPTQPVPNE-IEEAETYAEYEEYELLTNENS-- 192
            |::|...:|..|                 |..:.|...|.: ..|||...:.||.:..|.|:|
Human   475 VKNGQAPETCPFFEEMDALVSVRVAAPPNDGQEETASCPVQGTSEAEAQKQAEEADEATEEDSDD 539

  Fly   193 ----------------PEIAQEKGSTGTDVATEEPPEEEIAEDI------LDSDEDYDPTH---A 232
                            |.:.|...........|:..:.:|:|::      |...|...|.:   .
Human   540 DEEDTEIPPGAVITRAPVLFQSPRGFEAGFENEDNSKRDISEEVQLHRTLLARSERKIPRYLHQG 604

  Fly   233 KPEKCD-RSGR---------------------------------KPVAYHKNSPKVETFKKKVGR 263
            |..:.| ||||                                 :|..|.|       :.|..|
Human   605 KGNESDCRSGRQWAKTSGEKRGKLTLPEKSLSEVLSQQRPCLGERPYKYLK-------YSKSFG- 661

  Fly   264 KPRNKL---------STYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHM 319
             |.:.|         :.|.|..||..:...|||..|.:.|:|.||::|..||:.|..:...:.|.
Human   662 -PNSLLMHQVSHQVENPYKCADCGKSFSRSARLIRHRRIHTGEKPYKCLDCGKSFRDSSNFITHR 725

  Fly   320 NTHTGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPH 384
            ..|||.:||:|..|...|...|:...|.|.||.|:||.|:.|.::|..|.:...|:.|||||:||
Human   726 RIHTGEKPYQCGECGKCFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNSSHFSAHRRIHTGERPH 790

  Fly   385 VCDLCGKGFVKAYKLRLHRETH 406
            ||..|||.|.|:..||.|..||
Human   791 VCPDCGKSFSKSSDLRAHHRTH 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trem	NP_650861.1	zf-AD	11..87	CDD:214871
		COG5048	<264..411	CDD:227381	59/152 (39%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		zf-H2C2_2	287..311	CDD:290200	10/23 (43%)
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		zf-H2C2_2	315..338	CDD:290200	8/22 (36%)
		C2H2 Zn finger	330..350	CDD:275368	6/19 (32%)
		zf-H2C2_2	345..367	CDD:290200	10/21 (48%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		zf-H2C2_2	370..394	CDD:290200	13/23 (57%)
		C2H2 Zn finger	386..406	CDD:275368	9/19 (47%)
ZSCAN29	NP_001359009.1	SCAN	14..124	CDD:128708
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..182
		Myb_DNA-bind_4	245..330	CDD:372747
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	347..400
		Myb_DNA-bind_4	408..493	CDD:372747	4/17 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	502..557		11/54 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	603..625		6/21 (29%)
		COG5048	<630..838	CDD:227381	64/192 (33%)
		C2H2 Zn finger	680..700	CDD:275368	7/19 (37%)
		C2H2 Zn finger	708..728	CDD:275368	5/19 (26%)
		C2H2 Zn finger	736..756	CDD:275368	6/19 (32%)
		C2H2 Zn finger	764..784	CDD:275368	5/19 (26%)
		C2H2 Zn finger	792..812	CDD:275368	9/19 (47%)
		C2H2 Zn finger	820..840	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000