DRSC/TRiP Functional Genomics Resources

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Protein Alignment trem and ZNF792

DIOPT Version :9

Sequence 1:NP_650861.1 Gene:trem / 42392 FlyBaseID:FBgn0038767 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_787068.3 Gene:ZNF792 / 126375 HGNCID:24751 Length:632 Species:Homo sapiens


Alignment Length:202 Identity:68/202 - (33%)
Similarity:98/202 - (48%) Gaps:31/202 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   230 THAKPEKCDRSG-----RKPVAYHK--------------------NSPKVETFKKKVGRKPRNKL 269
            |..||.:|...|     |..:.:||                    ||..::.::...|.:|    
Human   361 TGEKPYECSDCGKFFSQRSNLIHHKRVHTGRSAHECSECGKSFNCNSSLIKHWRVHTGERP---- 421

  Fly   270 STYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNYCP 334
              |.|:.||..:...|.|.:|...|:|.:||.|..||:.|.::..|::|...|||.|||:||.|.
Human   422 --YKCNECGKFFSHIASLIQHQIVHTGERPHGCGECGKAFSRSSDLMKHQRVHTGERPYECNECG 484

  Fly   335 AAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEKPHVCDLCGKGFVKAYKL 399
            ..|:..|:...|.|:||.||||.|..|.:.|..|.:|..|:.:||||:|:.|..|||.|.:...|
Human   485 KLFSQSSSLNSHRRLHTGERPYQCSECGKFFNQSSSLNNHRRLHTGERPYECSECGKTFRQRSNL 549

  Fly   400 RLHRETH 406
            |.|.:.|
Human   550 RQHLKVH 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tremNP_650861.1 zf-AD 11..87 CDD:214871
COG5048 <264..411 CDD:227381 57/143 (40%)
C2H2 Zn finger 274..294 CDD:275368 6/19 (32%)
zf-H2C2_2 287..311 CDD:290200 10/23 (43%)
C2H2 Zn finger 302..322 CDD:275368 6/19 (32%)
zf-H2C2_2 315..338 CDD:290200 11/22 (50%)
C2H2 Zn finger 330..350 CDD:275368 7/19 (37%)
zf-H2C2_2 345..367 CDD:290200 11/21 (52%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
zf-H2C2_2 370..394 CDD:290200 11/23 (48%)
C2H2 Zn finger 386..406 CDD:275368 8/19 (42%)
ZNF792NP_787068.3 KRAB 14..74 CDD:214630
KRAB 14..53 CDD:279668
C2H2 Zn finger 256..276 CDD:275368
C2H2 Zn finger 284..304 CDD:275368
C2H2 Zn finger 312..332 CDD:275368
zf-H2C2_2 324..349 CDD:290200
C2H2 Zn finger 340..360 CDD:275368
COG5048 <348..592 CDD:227381 68/202 (34%)
zf-H2C2_2 352..377 CDD:290200 5/15 (33%)
C2H2 Zn finger 368..388 CDD:275368 5/19 (26%)
C2H2 Zn finger 396..416 CDD:275368 2/19 (11%)
C2H2 Zn finger 424..444 CDD:275368 6/19 (32%)
C2H2 Zn finger 452..472 CDD:275368 6/19 (32%)
zf-H2C2_2 464..489 CDD:290200 12/24 (50%)
C2H2 Zn finger 480..500 CDD:275368 7/19 (37%)
zf-H2C2_2 492..517 CDD:290200 11/24 (46%)
C2H2 Zn finger 508..528 CDD:275368 6/19 (32%)
zf-H2C2_2 520..545 CDD:290200 12/24 (50%)
C2H2 Zn finger 536..556 CDD:275368 8/19 (42%)
zf-H2C2_2 548..573 CDD:290200 4/9 (44%)
C2H2 Zn finger 564..584 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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