DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4854 and ZNF764

DIOPT Version :9

Sequence 1:NP_650860.1 Gene:CG4854 / 42391 FlyBaseID:FBgn0038766 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_219363.2 Gene:ZNF764 / 92595 HGNCID:28200 Length:408 Species:Homo sapiens


Alignment Length:258 Identity:69/258 - (26%)
Similarity:104/258 - (40%) Gaps:52/258 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 DEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEESV 157
            |..:::.|.:.|   :.|.||:               ||..:.||..:..|.|.:...:.|....
Human   102 DPADSRNKKKER---QREGTGA---------------LEKPDPVAAGSPGLKSPQAPSAGPPYGW 148

  Fly   158 YSLSP------------KPVTFEDEDSG----------------------QAASFTCNICNNVYS 188
            ..||.            .||...|:..|                      ....|.|..|...:.
Human   149 EQLSKAPHRGRPSLCAHPPVPRADQRHGCYVCGKSFAWRSTLVEHVYSHTGEKPFHCTDCGKGFG 213

  Fly   189 ERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQ 253
            ....|:.|..:|..::||.|..|.:.|.|...|..|:..|||.:||.|..|..||:..|...:|:
Human   214 HASSLSKHRAIHRGERPHRCLECGRAFTQRSALTSHLRVHTGEKPYGCADCGRRFSQSSALYQHR 278

  Fly   254 RIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHEKSHKRTK 316
            |:|:.|.|:.|..|.|:|.|.:.||.|::|||||:|:.|..|.:.|.|.....:|.::|...|
Human   279 RVHSGETPFPCPDCGRAFAYPSDLRRHVRTHTGEKPYPCPDCGRCFRQSSEMAAHRRTHSGEK 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4854NP_650860.1 zf-AD 12..>57 CDD:285071
C2H2 Zn finger 180..200 CDD:275368 4/19 (21%)
zf-H2C2_2 193..217 CDD:290200 8/23 (35%)
COG5048 201..>258 CDD:227381 21/56 (38%)
C2H2 Zn finger 208..228 CDD:275368 6/19 (32%)
zf-H2C2_2 221..244 CDD:290200 10/22 (45%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
zf-H2C2_2 251..273 CDD:290200 9/21 (43%)
C2H2 Zn finger 264..284 CDD:275368 8/19 (42%)
zf-H2C2_2 277..301 CDD:290200 12/23 (52%)
C2H2 Zn finger 292..312 CDD:275368 5/19 (26%)
ZNF764NP_219363.2 zf-H2C2_2 301..326 CDD:290200 12/24 (50%)
C2H2 Zn finger 317..337 CDD:275368 5/19 (26%)
zf-H2C2_2 333..352 CDD:290200 3/9 (33%)
C2H2 Zn finger 345..365 CDD:275368
KRAB 26..85 CDD:214630
KRAB 26..65 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 91..167 15/82 (18%)
C2H2 Zn finger 177..197 CDD:275368 0/19 (0%)
zf-H2C2_2 190..212 CDD:290200 3/21 (14%)
C2H2 Zn finger 205..225 CDD:275368 4/19 (21%)
zf-H2C2_2 217..242 CDD:290200 8/24 (33%)
COG5048 229..>294 CDD:227381 25/64 (39%)
C2H2 Zn finger 233..253 CDD:275368 6/19 (32%)
zf-H2C2_2 245..270 CDD:290200 11/24 (46%)
C2H2 Zn finger 261..281 CDD:275368 7/19 (37%)
zf-H2C2_2 273..298 CDD:290200 9/24 (38%)
COG5048 285..>350 CDD:227381 22/57 (39%)
C2H2 Zn finger 289..309 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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