DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and CG18764

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	408	Identity:	100/408 - (24%)
Similarity:	152/408 - (37%)	Gaps:	118/408 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LKCRIC--LV---QPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRS 69
            |:||.|  ::   .||:...:..|....| |...||..|...|:.|:.||..|.|.|..|:..|.
  Fly     3 LQCRTCGSIIYNKMPKNLFHIENEKMLQD-INLVTGTTLHNDPELPSSICACCTLDLNQAILFRE 66

  Fly    70 LCQQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDL-----------------------SKNEA 111
            .|..|:|            ::||..:..:.|..:.|:                       |..|.
  Fly    67 RCILTQK------------QLVHRRRSPEAKEPAEDVEEMASPPDCLNDPFGEVDEYIVESPEEV 119

  Fly   112 TGSDSELEYE-----YLDSY----------DVTLESSEDV-------------ACSADE------ 142
            ...||:..::     |:||.          :|..|.|:||             .|:.|.
  Fly   120 LDHDSDAHHDLDEDNYIDSVEDVDALQDMAEVAEEDSQDVESLISSVQKELESICNDDSNSDNND 184

  Fly   143 -----------------LVSIEPAISAPE-ESVYSLSPKPVTFEDEDSGQAASF----------- 178
                             .||..|....|| :|....|.||.|.:.:...|..::
  Fly   185 YMEPQNGSYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIER 249

  Fly   179 ---------TCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMN-THTGNRP 233
                     .|..|...::::.....||..|:..|...|:.|.|||.....:..|.. .|.|.:|
  Fly   250 KRLQRKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKP 314

  Fly   234 YKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKS 298
            |.|.:|...|.:.:||:.|:|.|||.:||.|..|.:.|..::..:.|...|||.|.|:|..|::|
  Fly   315 YDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQS 379

  Fly   299 FSQLHHKNSHEKSHKRTK 316
            |    .:|:|.|:|.|:|
  Fly   380 F----QRNTHLKAHLRSK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	15/49 (31%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		zf-H2C2_2	193..217	CDD:290200	9/23 (39%)
		COG5048	201..>258	CDD:227381	19/57 (33%)
		C2H2 Zn finger	208..228	CDD:275368	6/20 (30%)
		zf-H2C2_2	221..244	CDD:290200	7/23 (30%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		zf-H2C2_2	251..273	CDD:290200	10/21 (48%)
		C2H2 Zn finger	264..284	CDD:275368	4/19 (21%)
		zf-H2C2_2	277..301	CDD:290200	10/23 (43%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	23/83 (28%)
		C2H2 Zn finger	260..280	CDD:275368	4/19 (21%)
		zf-H2C2_2	272..297	CDD:290200	9/24 (38%)
		C2H2 Zn finger	288..309	CDD:275368	6/20 (30%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
		C2H2 Zn finger	345..365	CDD:275368	4/19 (21%)
		C2H2 Zn finger	373..391	CDD:275368	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960