Protein Alignment CG4854 and Zfp560

DIOPT Version :10

• Sequence 1: NP_650860.1
• Gene: CG4854 / 42391
• FlyBaseID: FBgn0038766
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001004190.2
• Gene: Zfp560 / 434377
• MGIID: 1915280
• Length: 754
• Species: Mus musculus
• Alignment Length: 345
• Identity: 90/345 - (26%)
• Similarity: 140/345 - (40%)
• Gaps: 100/345 - (28%)

  Fly    17 VQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLCQQTEKDLKEQ 81
            |.||:.|...|.|..     |..|.:.|                :.|:...::.|.|: |.::..
Mouse   184 VCPKETSSADTGPGL-----RQYGKDFS----------------MIASTAYQTTCVQS-KFIESS 226

  Fly    82 KLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDVACSADELVSI 146
            :.|:     |.|.|.          |.....||.||.:.            ||.|.|..    :.
Mouse   227 EFQQ-----VFDSQS----------SLQRPGGSHSEDKL------------SESVQCGD----TF 260

  Fly   147 EPAISAPEESVYSLSPKPVTFEDEDSGQAASFTCNI-----------------CNNVYSERVKLT 194
            .||:|..|.:......|  ::|.::.|::..::.|:                 |...:|....||
Mouse   261 SPALSHAESAQTCTGKK--SYECKECGKSFKYSANLNIHMRTHTGEKPYQCKECGKAFSRCYPLT 323

  Fly   195 NHMKVHSAKKPHECEICHKRFRQT----------------------------PQLARHMNTHTGN 231
            .|:|.|:.:||.||::|.|.||.:                            ..|::|:.||||.
Mouse   324 QHLKTHTEEKPFECKVCGKCFRNSSCLNDHFRVHTGIKPYKCKDCGKAFTGRSGLSKHLPTHTGE 388

  Fly   232 RPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQ 296
            :||:|..|...|...|..|||.:.|..|||::|:.|.::|..|:.|..||:|||||:||.||.|.
Mouse   389 KPYECKECGKAFPSTSGLIKHMKSHMGERPFECDHCGKAFASSSTLITHLRTHTGEKPFECQVCG 453

  Fly   297 KSFSQLHHKNSHEKSHKRTK 316
            |:|:...:...|.::|...|
Mouse   454 KAFTCSSYLRIHMRTHTGEK 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:214871	9/39 (23%)
		C2H2 Zn finger	180..200	CDD:275368	7/36 (19%)
		COG5048	201..>258	CDD:227381	24/84 (29%)
		C2H2 Zn finger	208..228	CDD:275368	7/47 (15%)
		zf-H2C2_2	221..244	CDD:463886	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		zf-H2C2_2	251..271	CDD:463886	8/19 (42%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		C2H2 Zn finger	292..312	CDD:275368	6/19 (32%)
Zfp560	NP_001004190.2	KRAB	41..97	CDD:214630
		COG5048	276..689	CDD:227381	60/200 (30%)
		C2H2 Zn finger	281..301	CDD:275368	2/19 (11%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		C2H2 Zn finger	337..357	CDD:275368	5/19 (26%)
		C2H2 Zn finger	365..385	CDD:275368	2/19 (11%)
		C2H2 Zn finger	393..413	CDD:275368	7/19 (37%)
		C2H2 Zn finger	421..441	CDD:275368	7/19 (37%)
		C2H2 Zn finger	449..469	CDD:275368	6/19 (32%)
		C2H2 Zn finger	477..497	CDD:275368
		C2H2 Zn finger	505..525	CDD:275368
		C2H2 Zn finger	533..553	CDD:275368
		C2H2 Zn finger	561..581	CDD:275368
		C2H2 Zn finger	589..609	CDD:275368
		C2H2 Zn finger	617..637	CDD:275368
		C2H2 Zn finger	645..665	CDD:275368
		C2H2 Zn finger	673..693	CDD:275368
		C2H2 Zn finger	701..718	CDD:275368