Protein Alignment CG4854 and trem

DIOPT Version :10

• Sequence 1: NP_650860.1
• Gene: CG4854 / 42391
• FlyBaseID: FBgn0038766
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_650861.1
• Gene: trem / 42392
• FlyBaseID: FBgn0038767
• Length: 439
• Species: Drosophila melanogaster
• Alignment Length: 419
• Identity: 128/419 - (30%)
• Similarity: 188/419 - (44%)
• Gaps: 116/419 - (27%)

  Fly     1 MHTNVDSRDLKCRICLVQPKD-ESLM--------PTEPDFPDKIKRCTGVELSESPDWPNRICTS 56
            |.|..:.:.:.||:||..|.: |.|:        .|..|  ..:..|.|:.:|...::|:::|:.
  Fly     1 MKTESNEKWVVCRVCLNNPSEGEELLHDIFSETASTRLD--QMLHICAGIPVSLDDNFPDKMCSK 63

  Fly    57 CALLLRAALKLRSLCQQT----------------------------------------------- 74
            |...||...|.|..||::
  Fly    64 CVRCLRLCYKFRLTCQRSHQHIMDMLDREASNANAAGEGDLLSIAEDLSVESVLKSWEDYASQLD 128

  Fly    75 -------EKDLKEQKL---------QEINIEIVHD----------EQETKKKTESRDLSKNE--- 110
                   |:|.:.|.:         .:.|:..|||          |.||..:.|..:|..||
  Fly   129 GGMKVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPVPNEIEEAETYAEYEEYELLTNENSP 193

  Fly   111 -------ATGSDSELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEE---------SVYS 159
                   :||:|...|....:      |.:||:..|.::   .:|..:.||:         :.:.
  Fly   194 EIAQEKGSTGTDVATEEPPEE------EIAEDILDSDED---YDPTHAKPEKCDRSGRKPVAYHK 249

  Fly   160 LSPKPVTFED----EDSGQAASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQ 220
            .|||..||:.    :...:.:::.|::|.|:|..:.:||.|||.||..||||||||.:.|.|..|
  Fly   250 NSPKVETFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQ 314

  Fly   221 LARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHT 285
            |.||||||||||||||:||.:.|||.||:.||.||||.||||.|:.|||:|.||:.|:.|...||
  Fly   315 LVRHMNTHTGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHT 379

  Fly   286 GERPFSCQYCQKSFSQLHHKNSHEKSHKR 314
            ||:|..|..|.|.|.:.:....|.::|.|
  Fly   380 GEKPHVCDLCGKGFVKAYKLRLHRETHNR 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:214871	14/53 (26%)
		C2H2 Zn finger	180..200	CDD:275368	9/19 (47%)
		COG5048	201..>258	CDD:227381	39/56 (70%)
		C2H2 Zn finger	208..228	CDD:275368	12/19 (63%)
		zf-H2C2_2	221..244	CDD:463886	17/22 (77%)
		C2H2 Zn finger	236..256	CDD:275368	11/19 (58%)
		zf-H2C2_2	251..271	CDD:463886	14/19 (74%)
		C2H2 Zn finger	264..284	CDD:275368	9/19 (47%)
		C2H2 Zn finger	292..312	CDD:275368	5/19 (26%)
trem	NP_650861.1	zf-AD	11..87	CDD:214871	21/77 (27%)
		COG5048	<264..411	CDD:227381	75/145 (52%)
		C2H2 Zn finger	274..294	CDD:275368	9/19 (47%)
		C2H2 Zn finger	302..322	CDD:275368	12/19 (63%)
		C2H2 Zn finger	330..350	CDD:275368	11/19 (58%)
		C2H2 Zn finger	358..378	CDD:275368	9/19 (47%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)