DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and CG4424

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	331	Identity:	111/331 - (33%)
Similarity:	167/331 - (50%)	Gaps:	40/331 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CRICL----------VQPKDESLMPTEPDFPDKIKRCTGVEL---SESPDWPNRICTSCALLLRA 63
            ||.||          .|..|:.| |......|||:..:|:::   ::....|.|||..|...|..
  Fly    11 CRTCLQDGEAHMVSIFQTADDRL-PGGVSLCDKIESLSGIQIRATAKEEVLPTRICLRCKAFLTL 74

  Fly    64 ALKLRSLCQQTEKDLKEQKL-----QEINIEIVHDEQETKKKT----ESRDLSKNEATGSDSELE 119
            |.|.|.:||::.:.|:|..:     |.:..|:|   |:|:..|    |:..|...|    |..||
  Fly    75 AHKFRQICQRSNEFLREYVIKDAVEQGVVKEVV---QQTRPSTPPPIETEQLEPPE----DEVLE 132

  Fly   120 YEYLDSYDVTLESSEDVA-CSADELVSIE--PAISAPEESVYSLSPKPVTFEDEDSGQAASFTCN 181
            .....:.|...|:....| .....::::|  ||...|..|    :|.|.   ...:.:.....|.
  Fly   133 EGVWSTEDPIEETPHGPAEKERPTVLTVEMLPAPYPPPAS----TPPPA---PAGAVKGKLHVCA 190

  Fly   182 ICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADP 246
            ||.|.|..:..|..||:.|:.::|:|||||||.|....||.||:..|||.:||.|.||...|||.
  Fly   191 ICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQRNFADR 255

  Fly   247 STRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHEKS 311
            ::.:||:|.|.|||||.|:.|.:.|.|::||::|.||||||:|..||.|.|||:::|:..:|.::
  Fly   256 TSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQT 320

  Fly   312 HKRTKE 317
            .:...:
  Fly   321 QQHIND 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	16/57 (28%)
		C2H2 Zn finger	180..200	CDD:275368	8/19 (42%)
		zf-H2C2_2	193..217	CDD:290200	13/23 (57%)
		COG5048	201..>258	CDD:227381	28/56 (50%)
		C2H2 Zn finger	208..228	CDD:275368	11/19 (58%)
		zf-H2C2_2	221..244	CDD:290200	11/22 (50%)
		C2H2 Zn finger	236..256	CDD:275368	9/19 (47%)
		zf-H2C2_2	251..273	CDD:290200	12/21 (57%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		zf-H2C2_2	277..301	CDD:290200	15/23 (65%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	24/81 (30%)
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		DUF45	<204..281	CDD:302795	38/76 (50%)
		COG5048	210..>345	CDD:227381	55/117 (47%)
		C2H2 Zn finger	217..237	CDD:275368	11/19 (58%)
		C2H2 Zn finger	245..265	CDD:275368	9/19 (47%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	15/23 (65%)
		C2H2 Zn finger	301..320	CDD:275368	8/18 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471441
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3C1GA
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26482
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.800