DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and CG31388

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	91/402 - (22%)
Similarity:	146/402 - (36%)	Gaps:	104/402 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CRIC-----------LVQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAAL 65
            ||.|           |..|...|::       .:|:..|.::|.|....|..:|..|...|:.|:
  Fly     5 CRTCSRMADPAVAKNLFDPSSSSVL-------RQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAI 62

  Fly    66 KLRSLC-----------QQTEKD------LKEQKLQEINIEI--------VHDEQETKKKTESRD 105
            ..|.:|           :|.||:      |.||.|.:...|:        ::|..:.....|.:|
  Fly    63 DFRRVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPEPQD 127

  Fly   106 LSKNEATGSDSELEYEYLDSYDVTLESSEDVACSADELVS-------IEPAISAPE--------- 154
            .:.:|.....:....||:::|............|.|..:|       :.|. |.||
  Fly   128 KNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPE-SEPESEAIDNRDT 191

  Fly   155 ESVYSLSPKPVTFEDEDSGQA-----------ASFTCNICNNVYSERVKLTNHMKV------HSA 202
            .|.::.|...:.||:.|..:.           ..|.|:.|:..:.....||.|..:      ||.
  Fly   192 SSSHTCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNMINLPLTHSC 256

  Fly   203 KK------------------------PHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRF 243
            .|                        .|.|.||.|.......|..|:..|.|.|.:|||.|.:.|
  Fly   257 TKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSASF 321

  Fly   244 ADPSTRIKHQRIHTNERPYKCEF-CSRSFGYSNVLRVHLKTH--TGERPFSCQYCQKSFSQLHHK 305
            ...:....||:.||.||||.|.: |.::|.:.:...:|.:.|  ..:|.:.|:||.||:......
  Fly   322 YTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKSYVTPSEC 386

  Fly   306 NSHEKSHKRTKE 317
            .:|:|.|..|::
  Fly   387 RTHQKYHNLTRD 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	12/55 (22%)
		C2H2 Zn finger	180..200	CDD:275368	5/25 (20%)
		zf-H2C2_2	193..217	CDD:290200	11/53 (21%)
		COG5048	201..>258	CDD:227381	20/80 (25%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		zf-H2C2_2	221..244	CDD:290200	9/22 (41%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		zf-H2C2_2	251..273	CDD:290200	11/22 (50%)
		C2H2 Zn finger	264..284	CDD:275368	4/20 (20%)
		zf-H2C2_2	277..301	CDD:290200	8/25 (32%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	17/77 (22%)
		C2H2 Zn finger	228..254	CDD:275368	5/25 (20%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	6/19 (32%)
		C2H2 Zn finger	342..363	CDD:275368	4/20 (20%)
		C2H2 Zn finger	373..393	CDD:275368	7/19 (37%)
		C2H2 Zn finger	401..419	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960