DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and CG8159

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	92/339 - (27%)
Similarity:	156/339 - (46%)	Gaps:	44/339 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CRICLVQPKDESLMPTEPDFPDK----IKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLCQ 72
            ||:|.....:...:........|    |...|||.|...|..|:.:|.:|...|::|:..|..|.
  Fly     6 CRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFRDRCL 70

  Fly    73 QTEKDLKEQKLQEINIEIVHDEQETKKKTESRD-----------LSKNEATGSDSELEYEYLDSY 126
            :::|..:|        .:|.:|::|.:.:..|.           ..|..|:..:..::.|.|.:.
  Fly    71 RSQKIFEE--------SLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPLEVMIKLESLSNG 127

  Fly   127 DVTLESSEDV----ACSADELVSIEPAISAPEESVYSLSP------------KPVTFEDEDSGQA 175
            |   |..:.:    :|:..::.....|:|:..|...:.||            |....|:......
  Fly   128 D---EEDDGIDHLDSCNEADMELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGGKGENRTKVTL 189

  Fly   176 ASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCD 240
            ..|.|:.|.|..:.:.....|::.||..:|.:||:|..||..:.:|..|...|||:|.::|.|||
  Fly   190 PVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVMHTGDRKFQCRYCD 254

  Fly   241 SRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHK 305
            ..:.:.|.|::|:|.|||:||:.|..|.:||..|.:|:.|:..|||||.|.|:.|.:||::..|.
  Fly   255 RTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHL 319

  Fly   306 NSHEKS--HKRTKE 317
            .:|.:|  ||...|
  Fly   320 KTHFRSNTHKHNLE 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	12/48 (25%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		zf-H2C2_2	193..217	CDD:290200	9/23 (39%)
		COG5048	201..>258	CDD:227381	22/56 (39%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	251..273	CDD:290200	11/21 (52%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-H2C2_2	277..301	CDD:290200	12/23 (52%)
		C2H2 Zn finger	292..312	CDD:275368	7/21 (33%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	18/71 (25%)
		C2H2 Zn finger	194..214	CDD:275368	4/19 (21%)
		COG5048	<197..322	CDD:227381	48/124 (39%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		zf-H2C2_2	265..287	CDD:290200	11/21 (52%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..315	CDD:290200	12/23 (52%)
		C2H2 Zn finger	306..328	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960