DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and nom

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	97/338 - (28%)
Similarity:	146/338 - (43%)	Gaps:	51/338 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CRIC----LVQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLC- 71
            ||:|    |.....|...|...|...:|:..||:.|.:.|:.|:.:|..|...|::|:..|..|
  Fly     6 CRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIFRRQCI 70

  Fly    72 ----------QQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSK-------------NEATG 113
                      |..:....|:|..|.|      :..|||||..|...:             ||:..
  Fly    71 LQQKKWVPLLQSDKVGASEEKKVEPN------DPSTKKKTTKRRRGRPRMPLEIVDIVVTNESKA 129

  Fly   114 SDSELEYEYLDSYDVTLE-SSEDVACSADELVSIEPAISAPEESVYSLSPKPVTFEDEDSGQAAS 177
            |..|....  |.:|..:| |:|..|..:|  |::| .|..|:|....        .|.|......
  Fly   130 SAGESVGG--DEFDQPVEISNEPDATDSD--VNLE-EIDLPDEDGLE--------SDHDLPNVQI 181

  Fly   178 FTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARH-MNTHTGNRPYKCDYCDS 241
            ..|:.|..:.:.:..|..|...|:..:|:.|:.|.|.|....:|..| :..||...|:.|.|||.
  Fly   182 HKCDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPKTFLVASELKAHNLTHHTLEPPFACRYCDR 246

  Fly   242 RFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKN 306
            |:.....|.||:|:||||||:.|:.|.::|..:.:|:.|:..|...|.:||..|.:|||...|..
  Fly   247 RYFSVVGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCDVCDRSFSLKKHLA 311

  Fly   307 SH--EKSHKRTKE 317
            :|  ..:|||..|
  Fly   312 THFISNTHKRNAE 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	14/48 (29%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		zf-H2C2_2	193..217	CDD:290200	8/23 (35%)
		COG5048	201..>258	CDD:227381	20/57 (35%)
		C2H2 Zn finger	208..228	CDD:275368	6/20 (30%)
		zf-H2C2_2	221..244	CDD:290200	10/23 (43%)
		C2H2 Zn finger	236..256	CDD:275368	9/19 (47%)
		zf-H2C2_2	251..273	CDD:290200	12/21 (57%)
		C2H2 Zn finger	264..284	CDD:275368	5/19 (26%)
		zf-H2C2_2	277..301	CDD:290200	9/23 (39%)
		C2H2 Zn finger	292..312	CDD:275368	7/21 (33%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	19/69 (28%)
		C2H2 Zn finger	184..204	CDD:275368	4/19 (21%)
		C2H2 Zn finger	212..261	CDD:275368	18/48 (38%)
		zf-H2C2_2	255..278	CDD:290200	12/22 (55%)
		C2H2 Zn finger	269..289	CDD:275368	5/19 (26%)
		zf-H2C2_2	282..305	CDD:290200	8/22 (36%)
		C2H2 Zn finger	297..313	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960