DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and CG14667

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	85/340 - (25%)
Similarity:	139/340 - (40%)	Gaps:	62/340 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CRIC----LVQPKDESL-MPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLC 71
            ||||    :...:|.:: :.....:..::|..|||||:.:...|..:|..|...|..|.|.|..|
  Fly     7 CRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATKFRERC 71

  Fly    72 QQTEKDLKEQKLQEINIEIVHDEQETKKKTESR-----DLSK---NEATGSDSELEYEYLDS--- 125
            ..::|.|         ::|:       |||..:     :||.   :|......:||..|.|.
  Fly    72 IFSQKYL---------LDII-------KKTSDQSTVHVELSSEPLDEQLIDADQLETHYDDDQYV 120

  Fly   126 -YDVTLESSEDVA-------CSADELVSIEPAISAPEESVYSLSPKPVTFEDEDSGQAAS----- 177
             |..|.|..:|:.       .||..:.:.|.|..|.::.         ..::::..:||.
  Fly   121 CYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEAAQQE---------DLQEQEMERAAKRRSNF 176

  Fly   178 FTCNICNNVYSERVKLTNHMKVHSAKKP----HECEICHKRFRQTPQLARH-MNTHTGNRPYKCD 237
            |.|:.|..::.:....|.|:..|..::.    ..|..|.:.|.:...|.:| ...|..||.::|.
  Fly   177 FICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCT 241

  Fly   238 YCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGE-RPFSCQYCQKSFSQ 301
            .|...||....:::|.:.|.|||||.|..|...|...:.|:.|..||:.: |.|.|:.|...|..
  Fly   242 ICHEAFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFIT 306

  Fly   302 LHHKNSHEKS--HKR 314
            .....:|.|:  |||
  Fly   307 RRGLVAHTKTAPHKR 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	13/49 (27%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		zf-H2C2_2	193..217	CDD:290200	6/27 (22%)
		COG5048	201..>258	CDD:227381	14/61 (23%)
		C2H2 Zn finger	208..228	CDD:275368	5/20 (25%)
		zf-H2C2_2	221..244	CDD:290200	7/23 (30%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		zf-H2C2_2	251..273	CDD:290200	10/21 (48%)
		C2H2 Zn finger	264..284	CDD:275368	5/19 (26%)
		zf-H2C2_2	277..301	CDD:290200	9/24 (38%)
		C2H2 Zn finger	292..312	CDD:275368	5/21 (24%)
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	21/81 (26%)
		C2H2 Zn finger	179..199	CDD:275368	4/19 (21%)
		C2H2 Zn finger	211..232	CDD:275368	5/20 (25%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	22/69 (32%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	297..316	CDD:275368	4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960